Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 5/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.45 |
| ▸ | GBA1 | P04062 | 7/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557057 | 0.97 | GNAI3 (0.47) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| SCHEMBL11794036 | 0.97 | GNAI3 (0.47) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| Bromide SCHEMBL28185708 | 0.95 | GNAI3 (0.46) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| Bromide SCHEMBL29089345 | 0.95 | GNAI3 (0.46) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| Bromide SCHEMBL28185105 | 0.95 | GNAI3 (0.46) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| SCHEMBL6028682 | 0.83 | KCNH2 (0.34) | GNAI3GNAO1GNAI1 | |
| SCHEMBL372823 | 0.83 | — | — | |
| Hydrazine SCHEMBL8554307 | 0.80 | KCNH2 (0.42) | — | |
| SCHEMBL5141998 | 0.77 | SLC6A2 (0.43) | — | |
| SCHEMBL1654781 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |