Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4991914 | 0.79 | HCAR3 (0.41) | HCAR3CSNK2A1CSNK2A2CSNK2BTSHR | |
| SCHEMBL4990576 | 0.78 | CSNK2A1 (0.54) | CSNK2A1CSNK2A2CSNK2BTP53 | |
| SCHEMBL4984420 | 0.78 | ALDH1A1 (0.60) | HCAR3CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL24312831 | 0.76 | SOD1 (0.55) | TP53 | |
| SCHEMBL4991890 | 0.75 | TSHR (0.50) | TP53TSHR | |
| SCHEMBL6649636 | 0.74 | HCAR3 (0.52) | HCAR3XDHTP53TSHR | |
| Hydrochloric Acid SCHEMBL10456360 | 0.73 | TSHR (0.48) | TP53TSHR | |
| SCHEMBL4991719 | 0.73 | HCAR3 (0.41) | HCAR3CSNK2A1CSNK2A2CSNK2BTSHR | |
| SCHEMBL4994161 | 0.72 | ALDH1A1 (0.60) | HCAR3CSNK2A1 | |
| SCHEMBL4986819 | 0.72 | CSNK2A1 (0.51) | CSNK2A1CSNK2A2CSNK2BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131656-A2 | PHTHALAZINE DERIVATIVES | Forest Laboratories Holdings Limited (BM) | 2009-12-16 | — | — | EP | claimed |
| WO-2008061108-A2 | PHTHALAZINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-05-22 | — | — | WO | claimed |