Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17204488 | 0.91 | IDO1 (0.38) | IDO1METAP2ATP4AATP4BDCUN1D1 | |
| O-Xylene SCHEMBL27600417 | 0.80 | ACHE (0.48) | CDK2GPBAR1CYP1A2CYP2C19MEN1 | |
| SCHEMBL3366129 | 0.78 | ALOX5AP (0.45) | IDO1METAP2ATP4AATP4BNPC1 | |
| SCHEMBL1782451 | 0.78 | IDO1 (0.44) | IDO1DCUN1D1CDK2RAB9ACYP1A2 | |
| SCHEMBL27814299 | 0.77 | HSP90AA1 (0.55) | METAP2ATP4AATP4BDCUN1D1CYP1A2 | |
| SCHEMBL20415004 | 0.76 | AGPAT2 (0.45) | IDO1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL25593137 | 0.76 | PLA2G7 (0.46) | IDO1CDK2RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL10304960 | 0.75 | IDO1 (0.42) | IDO1METAP2ATP4AATP4BKDM4E | |
| SCHEMBL28352850 | 0.74 | IDO1 (0.50) | IDO1CYP2D6 | |
| SCHEMBL319173 | 0.72 | CDK2 (0.48) | CDK2NPC1RAB9ACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363702-A4 | METHODS OF INHIBITING KINASES | CYTOPIA PTY LTD (AU) | 2007-08-22 | — | — | EP | disclosed |
| US-20060069084-A1 | Methods of inhibiting kinases | CYTOPIA RESEARCH PTY LTD (AU) | 2006-03-30 | — | — | US | disclosed |
| US-20040102455-A1 | Method of inhibiting kinases | CYTOPIA RESEARCH PTY LTD (AU) | 2004-05-27 | — | — | US | disclosed |
| EP-1363702-A1 | METHODS OF INHIBITING KINASES | Cytopia PTY Ltd (AU) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002060492-A1 | METHODS OF INHIBITING KINASES | CYTOPIA PTY LTD (AU) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102455-A1 | Method of inhibiting kinases | JAK2, JAK1, JAK3 | IDO1 581/4885METAP2 1923/4885ATP4A 4541/4885 |
| US-20060069084-A1 | Methods of inhibiting kinases | JAK2, JAK1, JAK3 | IDO1 661/4885METAP2 1985/4885ATP4A 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.