Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516955 | 0.81 | SIGMAR1 (0.67) | OPRM1OPRK1SIGMAR1CHRNA7KMT2A | |
| SCHEMBL6305743 | 0.81 | CCR3 (0.62) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL6305745 | 0.81 | CCR3 (0.62) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10368353 | 0.79 | OPRM1 (0.69) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10366240 | 0.77 | SIGMAR1 (0.56) | OPRM1OPRK1SIGMAR1HPGDKMT2A | |
| SCHEMBL8678608 | 0.77 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL422065 | 0.77 | OPRM1 (0.47) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10189516 | 0.77 | OPRM1 (0.47) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL422064 | 0.77 | OPRM1 (0.47) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL20812406 | 0.76 | HPGD (0.68) | HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534299-A4 | METHODS FOR TREATING PSYCHOSIS ASSOCIATED WITH INTERFERON-ALPHA THERAPY | CORCEPT THERAPEUTICS INC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1534299-A2 | METHODS FOR TREATING PSYCHOSIS ASSOCIATED WITH INTERFERON-ALPHA THERAPY | Corcept Therapeutics, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004004653-A2 | METHODS FOR TREATING PSYCHOSIS ASSOCIATED WITH INTERFERON-ALPHA THERAPY | CORCEPT THERAPEUTICS, INC. (US) | 2004-01-15 | — | — | WO | disclosed |