Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366530 | 0.85 | OPRM1 (0.48) | OPRM1OPRK1 | |
| SCHEMBL8678608 | 0.83 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10368802 | 0.79 | OPRM1 (0.57) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL5142329 | 0.79 | OPRM1 (0.61) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10368909 | 0.76 | OPRM1 (0.41) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10367904 | 0.75 | OPRM1 (0.40) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10366782 | 0.72 | SIGMAR1 (0.53) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9516955 | 0.71 | SIGMAR1 (0.67) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10366240 | 0.70 | SIGMAR1 (0.56) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10189797 | 0.68 | OPRM1 (0.51) | OPRM1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147085-B1 | SUBSTITUTED TRANS-1.2-DIAMINOCYCLOHEXYL AMIDE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1990-03-14 | — | — | EP | claimed |