SCHEMBL514267

SCHEMBL514267

CSc1ccccc1O[C]=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 5/20 0.38
HSD17B10 Q99714 1/20 0.38
AR P10275 1/20 0.37
MAPT P10636 4/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KMT2A Q03164 5/20 0.33
MEN1 O00255 4/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
MDM2 Q00987 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21812167 0.79 AR (0.43) POLBTSHRSMN1; SMN2HSD17B10AR
SCHEMBL6571065 0.77 CA1 (0.38) TSHRSMN1; SMN2TDP1HPGDALDH1A1
SCHEMBL2774997 0.75 SLC6A2 (0.49) POLBTSHRSMN1; SMN2HSD17B10AR
SCHEMBL27549965 0.75 POLB (0.38) POLBTSHRSMN1; SMN2HSD17B10AR
SCHEMBL515463 0.75 MAPT (0.40) POLBTSHRSMN1; SMN2HSD17B10AR
SCHEMBL1456050 0.75 GAA (0.33) POLBTSHRSMN1; SMN2HSD17B10MAPT
SCHEMBL7828379 0.73 CCR2 (0.33) TSHRTDP1L3MBTL1ALDH1A1SLC6A2
SCHEMBL25820737 0.73 POLB (0.42) POLBTSHRSMN1; SMN2HSD17B10AR
SCHEMBL71009 0.73 CA1 (0.57) POLBTSHRSMN1; SMN2HSD17B10AR
SCHEMBL30514820 0.73 CA1 (0.57) POLBTSHRSMN1; SMN2HSD17B10AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed
US-7572907-B2 Methods and compounds for polynucleotide synthesis AGILENT TECHNOLOGIES, INC. (US) 2009-08-11 US disclosed
EP-1717242-A1 Polynucleotide synthesis Agilent Technologies, Inc. (US) 2006-11-02 EP disclosed
US-20060247430-A1 Methods and compounds for polynucleotide synthesis AGILENT TECHNOLOGIES, INC. 2006-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247430-A1 Methods and compounds for polynucleotide synthesis POLN, POLRMT, POLM POLB 4/4885TSHR 3633/4885SMN1; SMN2 185/4885
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 POLB 4117/4885TSHR 307/4885SMN1; SMN2 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.