⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515004 | 0.91 | — | — | |
| SCHEMBL4942561 | 0.88 | FAAH (0.56) | — | |
| SCHEMBL1679627 | 0.88 | FAAH (0.56) | — | |
| SCHEMBL6378120 | 0.88 | FAAH (0.56) | — | |
| SCHEMBL514742 | 0.80 | — | — | |
| SCHEMBL52570 | 0.73 | CA2 (0.52) | — | |
| SCHEMBL2667216 | 0.73 | — | — | |
| SCHEMBL162117 | 0.71 | — | — | |
| SCHEMBL28606255 | 0.71 | CA2 (0.50) | — | |
| SCHEMBL514270 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929519-B1 | BETA-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | UPJOHN CO (US) | 2005-02-23 | — | — | EP | claimed |
| US-6235928-B1 | ENZYME INHIBITOR MATRIX METALLOPROTEINASE FAMILY, INCLUDING COLLAGENASE, STROMELYSIN, AND GELATINASE, THE COMPOUNDS OR PHARMACEUTICAL COMPOSITIONS | PHARMACIA & UPJOHN COMPANY | 2001-05-22 | — | — | US | claimed |
| EP-0929519-A1 | $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-21 | — | — | EP | claimed |
| US-5847153-A | β-sulfonyl hydroxamic acids | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | claimed |
| WO-1998013340-A1 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-02 | — | — | WO | claimed |
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | claimed |
| EP-4382100-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | Eurofarma Laboratórios S.A. (BR) | 2024-06-12 | — | — | EP | disclosed |
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3892278-B1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-20230074669-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-03-09 | — | — | US | disclosed |
| US-20230030720-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-02-02 | — | — | US | disclosed |
| US-5518994-A | 2-arylaminopyrimidinone derivative, and herbicide and plant growth regulator | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0636615-A1 | 2-ARYLAMINOPYRIMIDINONE DERIVATIVE, AND HERBICIDE AND PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-4909833-A | A 4-chlorophenyl ring substituted in position 1 of a triazolin-5-one ring | NIHON NOHYAKU CO., LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0095836-B1 | AZA-FUROCHROMONES | THE UPJOHN COMPANY (US) | 1986-08-13 | — | — | EP | disclosed |
| EP-0099172-B1 | 6,7-DIHYDRO-7,7-DISUBSTITUTED-KHELLINS | THE UPJOHN COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| US-4434295-A | Anti-atherosclerotic 6,7-dihydro-7,7-disubstituted-khellin analogs | THE UPJOHN COMPANY (US) | 1984-02-28 | — | — | US | disclosed |
| US-4412071-A | Antiatherosclerotic compositions | THE UPJOHN COMPANY (US) | 1983-10-25 | — | — | US | disclosed |