Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942561 | 1.00 | FAAH (0.56) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL6378120 | 1.00 | FAAH (0.56) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL515004 | 0.97 | — | — | |
| SCHEMBL514269 | 0.88 | — | — | |
| SCHEMBL11058951 | 0.77 | CA2 (0.68) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL350042 | 0.77 | CA2 (0.68) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL5586100 | 0.77 | CA2 (0.68) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL395321 | 0.77 | CA2 (0.68) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL10946867 | 0.77 | FAAH (0.62) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL5379286 | 0.77 | CA2 (0.68) | FAAHCA2TSHRTHRBCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | claimed |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| US-11964957-B2 | Pyrazole derivative and harmful organism-controlling agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| EP-3808738-B1 | PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2024-04-17 | — | — | EP | disclosed |
| CN-112236421-B | Pyrazole derivatives and pest control agents | 组合化学工业株式会社 | 2023-12-26 | — | — | CN | disclosed |
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-02 | — | — | US | disclosed |
| CN-110612295-B | Pyrazole-3-carboxylic acid amide derivative and pest control agent | 组合化学工业株式会社 | 2023-07-14 | — | — | CN | disclosed |
| US-20230110603-A1 | 3-ALKOXYBENZAMIDE DERIVATIVE, AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-04-13 | — | — | US | disclosed |
| EP-3623365-B1 | PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2023-01-04 | — | — | EP | disclosed |
| EP-4098650-A1 | 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2022-12-07 | — | — | EP | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |
| EP-0095836-B1 | AZA-FUROCHROMONES | THE UPJOHN COMPANY (US) | 1986-08-13 | — | — | EP | disclosed |
| EP-0099172-B1 | 6,7-DIHYDRO-7,7-DISUBSTITUTED-KHELLINS | THE UPJOHN COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| US-4434295-A | Anti-atherosclerotic 6,7-dihydro-7,7-disubstituted-khellin analogs | THE UPJOHN COMPANY (US) | 1984-02-28 | — | — | US | disclosed |
| EP-0095836-A1 | Aza-furochromones | THE UPJOHN COMPANY (US) | 1983-12-07 | — | — | EP | disclosed |
| US-4412071-A | Antiatherosclerotic compositions | THE UPJOHN COMPANY (US) | 1983-10-25 | — | — | US | disclosed |
| EP-0014386-A2 | Phosphoramido(di)thioate derivatives, processes for their preparation and pesticidal compositions containing them, as well as intermediates | ROHM AND HAAS COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | CYP2C19, CYP3A7, CYP3A5 | FAAH 4577/4885CA2 1930/4885TSHR 2282/4885 |
| US-11964957-B2 | Pyrazole derivative and harmful organism-controlling agent | L3MBTL3, L3MBTL1, L3MBTL4 | FAAH 3693/4885CA2 1131/4885TSHR 870/4885 |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | H1-3, HDAC3, H1-0 | FAAH 60/4885CA2 275/4885TSHR 297/4885 |
| US-20230110603-A1 | 3-ALKOXYBENZAMIDE DERIVATIVE, AND PEST CONTROL AGENT | CBR3, ALK, BRS3 | FAAH 33/4885CA2 36/4885TSHR 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.