Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336406 | 0.87 | PPARA (0.46) | P2RX7LMNAMEN1KMT2ACA1 | |
| SCHEMBL6485285 | 0.84 | P2RX7 (0.53) | P2RX7LMNAMEN1KMT2ACA1 | |
| SCHEMBL5334659 | 0.83 | CYP4F2 (0.46) | P2RX7LMNAMEN1KMT2ACA1 | |
| SCHEMBL4116624 | 0.82 | P2RX7 (0.64) | P2RX7LMNAMEN1KMT2ACA1 | |
| Hydrochloric Acid SCHEMBL5960230 | 0.81 | P2RX7 (0.64) | P2RX7LMNAMEN1KMT2ACA1 | |
| Hydrochloric Acid SCHEMBL5924089 | 0.81 | P2RX7 (0.64) | P2RX7LMNAMEN1KMT2ACA1 | |
| SCHEMBL8081000 | 0.81 | CA1 (0.55) | P2RX7LMNAMEN1KMT2ACA1 | |
| SCHEMBL5333690 | 0.80 | P2RX7 (0.52) | NPC1RAB9AP2RX7LMNAMEN1 | |
| SCHEMBL7554542 | 0.80 | EPHX2 (0.49) | P2RX7LMNAMEN1KMT2ACA1 | |
| SCHEMBL7658512 | 0.80 | P2RX7 (0.54) | P2RX7LMNAMEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297818-B2 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2007-11-20 | — | — | US | disclosed |