Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4116624 | 0.92 | P2RX7 (0.64) | P2RX7CA1CA2LMNATP53 | |
| Hydrochloric Acid SCHEMBL5924089 | 0.91 | P2RX7 (0.64) | P2RX7CA1CA2LMNATP53 | |
| Hydrochloric Acid SCHEMBL5960230 | 0.91 | P2RX7 (0.64) | P2RX7CA1CA2LMNATP53 | |
| SCHEMBL2462791 | 0.86 | ABCB11 (0.52) | P2RX7CA1CA2MEN1KMT2A | |
| SCHEMBL5336406 | 0.85 | PPARA (0.46) | P2RX7CA1CA2LMNATP53 | |
| SCHEMBL5142841 | 0.84 | NPC1 (0.44) | P2RX7CA1CA2LMNATP53 | |
| SCHEMBL5446631 | 0.84 | P2RX7 (0.41) | P2RX7CA1CA2LMNATP53 | |
| Methane SCHEMBL14735926 | 0.84 | ABCB11 (0.52) | P2RX7CA1CA2MEN1KMT2A | |
| SCHEMBL5334659 | 0.84 | CYP4F2 (0.46) | P2RX7CA1CA2LMNATP53 | |
| SCHEMBL5333690 | 0.83 | P2RX7 (0.52) | P2RX7CA1CA2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881754-B2 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2005-04-19 | — | — | US | disclosed |