SCHEMBL2439283

SCHEMBL2439283

CN1C=CC(c2c3nc(cc4ccc(cc5nc(cc6ccc2[nH]6)C=C5)[nH]4)C=C3)=CC1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.46
STAT1 P42224 1/20 0.46
TERT O14746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8182072 0.96 STAT3 (0.44) STAT3STAT1TERT
Acetic Acid SCHEMBL9582363 0.94 STAT3 (0.44) STAT3STAT1
Acetic Acid SCHEMBL9582779 0.94 STAT3 (0.44) STAT3STAT1
SCHEMBL9583481 0.90 STAT3 (0.40) STAT3STAT1TERT
Hydrochloric Acid SCHEMBL13274495 0.88 STAT3 (0.53) STAT3STAT1TERT
SCHEMBL5143471 0.85 STAT3 (0.44) STAT3STAT1
SCHEMBL19718106 0.82 STAT3 (0.39) STAT3STAT1
SCHEMBL29677253 0.82 TERT (0.44) TERT
SCHEMBL18418 0.82 TERT (0.44) TERT
SCHEMBL2439280 0.82 STAT3 (0.30) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006021403-A1 BICYCLONONENE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2006-03-02 WO claimed
US-6620805-B1 Drug delivery of antihepatitis viricide to hepatocytes YALE UNIVERSITY 2003-09-16 US claimed
US-6610478-B1 Delivering nucleic acids to bacterial cells. The method does not require manipulation of the bacteria and is therefore particularly suited to delivery of nucleic acids to bacteria in natural environments such as bodies of animals YALE UNIVERSITY 2003-08-26 US claimed
US-12011611-B2 Illumination devices for inducing biological effects KNOW BIO, LLC (US) 2024-06-18 US disclosed
US-11986666-B2 Illumination devices for inducing biological effects KNOW BIO, LLC (US) 2024-05-21 US disclosed
EP-4362943-A2 NEW DRUG APPLICATION Centre National de la Recherche Scientifique (FR) 2024-05-08 EP disclosed
US-20240075312-A1 ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS KNOW BIO, LLC 2024-03-07 US disclosed
US-20240024699-A1 ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS KNOW BIO LLC (US) 2024-01-25 US disclosed
US-20230302144-A1 Porphyrin Compounds and Compositions Useful for Treating Cancer ONCOSELECT THERAPEUTICS, LLC (US) 2023-09-28 US disclosed
US-20230302293-A1 ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS KNOW BIO LLC (US) 2023-09-28 US disclosed
US-11752359-B2 Illumination devices for inducing biological effects KNOW BIO, LLC (US) 2023-09-12 US disclosed
EP-0726781-B1 IN VIVO AGENTS COMPRISING RADIOACTIVE METAL-ION CHELATES WITH ACIDIC SACCHARIDES AND GLYCOSAMINOGLYCANS, GIVING IMPROVED SITE-SELECTIVE LOCALIZATION, UPTAKE MECHANISM, SENSITIVITY AND KINETIC-SPATIAL PROFILES ACCESS PHARMA INC (US) 2001-08-22 EP disclosed
WO-2001054764-A2 BIOABSORBABLE BRACHYTHERAPY DEVICE BIOSURFACE ENGINEERING TECHNOLOGIES, INC (US) 2001-08-02 WO disclosed
EP-0894011-A2 DELIVERY OF NUCLEIC ACIDS BY PORPHYRINS INNOVIR LABORATORIES, INC. (US) 1999-02-03 EP disclosed
WO-1997033622-A2 DELIVERY OF NUCLEIC ACIDS BY PORPHYRINS INNOVIR LABORATORIES, INC. (US) 1997-09-18 WO disclosed
EP-0345171-B1 Metalloporphyrine derivatives, their therapeutical use and their use in the preparation of hybrid molecules CENTRE NAT RECH SCIENT (FR) 1995-12-13 EP disclosed
US-5236914-A Antitumor agents, viricides CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1993-08-17 US disclosed
US-5230998-A Viricides AIDA DEVELOPMENT CORPORATION 1993-07-27 US disclosed
WO-1989012049-A1 DERIVATIVES OF METALLOPORPHYRINES, THEIR PREPARATION, APPLICATION FOR THERAPEUTICAL PURPOSES AND USE IN PREPARING HYBRID MOLECULES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 1989-12-14 WO disclosed
EP-0345171-A1 Metalloporphyrine derivatives, their therapeutical use and their use in the preparation of hybrid molecules CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1989-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230302144-A1 Porphyrin Compounds and Compositions Useful for Treating Cancer KIT, HCCS, PPIF STAT3 1427/4885STAT1 4192/4885TERT 932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.