Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18920885 | 0.78 | CYP2C9 (0.45) | KDM4EALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL120954 | 0.78 | CA12 (0.51) | KDM4EALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL31297525 | 0.78 | CA12 (0.51) | KDM4EALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL13617189 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1GAANPC1MAPT | |
| SCHEMBL13562292 | 0.76 | CYP2C9 (0.44) | KDM4EALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL7346302 | 0.74 | GAA (0.62) | KDM4EALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL17994122 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1GAANPC1MAPT | |
| SCHEMBL9524554 | 0.72 | ABCG2 (0.66) | KDM4EALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL2349072 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1GAANPC1MAPT | |
| SCHEMBL3537107 | 0.71 | CYP2C9 (0.50) | KDM4ENPC1KMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040261198-A1 | Restructuring and finishing of keratin fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-12-30 | — | — | US | claimed |
| EP-1455736-A1 | RESTRUCTURING AND FINISHING OF KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-09-15 | — | — | EP | claimed |
| WO-2003053375-A1 | RESTRUCTURING AND FINISHING OF KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-07-03 | — | — | WO | claimed |
| US-7161010-B2 | Methine dyes; coloring compound | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20070004923-A1 | Methine compound and silver halide photographic material containing the same | FUJI PHOTO FILM CO., LTD. | 2007-01-04 | — | — | US | disclosed |
| EP-0953634-B1 | COMPOSITION FOR TREATING POROUS ARTICLE, TREATMENT METHOD, AND USE THEREOF | SDS BIOTECH CORP (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-20040261198-A1 | Restructuring and finishing of keratin fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-12-30 | — | — | US | disclosed |
| EP-1455736-A1 | RESTRUCTURING AND FINISHING OF KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-09-15 | — | — | EP | disclosed |
| US-20040063962-A1 | Methine compound and silver halide photographic material containing the same | FUJI PHOTO FILM CO., LTD. | 2004-04-01 | — | — | US | disclosed |
| US-6667405-B2 | Nitrogen containing heterocyclilc compound and quaternary salt compound which are raw material of the methine dye, useful as coloring agent, a light absorber, for an optical disc or marker for diagnosis | FUJI PHOTO FILM CO., LTD. (JP) | 2003-12-23 | — | — | US | disclosed |
| WO-2003053375-A1 | RESTRUCTURING AND FINISHING OF KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-07-03 | — | — | WO | disclosed |
| US-20030017565-A1 | COMPOSITION AND METHOD FOR TREATING A POROUS ARTICLE AND USE THEREOF | SDS BIOTECH K.K. (JP) | 2003-01-23 | — | — | US | disclosed |
| US-20020076666-A1 | Methine compound and silver halide photographic material containing the same | FUJI PHOTO FILM CO., LTD. | 2002-06-20 | — | — | US | disclosed |
| US-6333146-B1 | METHINE DYE WHICH IS USEFUL AS A COLORING AGENT, A LIGHT ABSORBER, A DYE FOR AN OPTICAL DISC, SPECTRAL SENSITIZING DYES FOR A SILVER HALIDE PHOTOGRAPH, AN ELECTROPHOTOGRAPH AND A PHOTOELECTRIC CONVERSION DEVICE, OR A MARKER FOR DIAGNOSIS | FUJI PHOTO FILM CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-0953634-A1 | COMPOSITION FOR TREATING POROUS ARTICLE, TREATMENT METHOD, AND USE THEREOF | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1999-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004923-A1 | Methine compound and silver halide photographic material containing the same | PYM1, NPM1, METTL3 | KDM4E 2044/4885ALDH1A1 172/4885GAA 3792/4885 |
| US-20020076666-A1 | Methine compound and silver halide photographic material containing the same | PYM1, NPM1, METTL3 | KDM4E 1595/4885ALDH1A1 264/4885GAA 3679/4885 |
| US-20040063962-A1 | Methine compound and silver halide photographic material containing the same | PYM1, NPM1, METTL3 | KDM4E 1635/4885ALDH1A1 269/4885GAA 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.