Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605891 | 0.88 | ADRB3 (0.66) | ADRB3 | |
| SCHEMBL7040736 | 0.86 | ADRB3 (0.69) | ADRB3ADRB2 | |
| SCHEMBL7638524 | 0.86 | ADRB3 (0.78) | ADRB3 | |
| SCHEMBL7039229 | 0.85 | ADRB3 (0.64) | ADRB3ADRB2ADRB1 | |
| SCHEMBL27456146 | 0.84 | ADRB3 (0.69) | ADRB3 | |
| SCHEMBL7039234 | 0.83 | ADRB3 (0.65) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7610750 | 0.83 | ADRB3 (0.69) | ADRB3ADRB2 | |
| SCHEMBL7605269 | 0.83 | ADRB3 (0.69) | ADRB3ADRB2 | |
| SCHEMBL7036007 | 0.82 | ADRB3 (0.67) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7037458 | 0.82 | ADRB3 (0.66) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217706-B2 | Propanolamine derivatives | ASTELLAS PHARMA INC. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20020120148-A1 | Propanolamine derivatives | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120148-A1 | Propanolamine derivatives | AMY2A, PNMT, PNLIP | ADRB3 12/4885ADRB2 7/4885ADRB1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.