SCHEMBL5144048

SCHEMBL5144048

O=COCCOC(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.63
LMNA P02545 2/20 0.59
MAPK1 P28482 1/20 0.52
HIF1A Q16665 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KMT2A Q03164 1/20 0.52
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
ALDH1A1 P00352 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
TSHR P16473 1/20 0.47
F2 P00734 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14391140 0.95 TDP1 (0.58) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL6882856 0.88 TDP1 (0.73) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL137486 0.86 TDP1 (0.83) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL16217656 0.84 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL13292516 0.84 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL28286830 0.84 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL547137 0.84 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2
Butyl Formate SCHEMBL27602214 0.84 LMNA (0.63) TDP1LMNAMAPK1ESR1ALDH1A1
SCHEMBL11609595 0.84 LMNA (0.62) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL2978166 0.84 TDP1 (0.61) TDP1LMNAMAPK1HIF1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130045340-A1 CELLULOSE ACETATE FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE WHICH ARE MADE USING SAME KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-02-21 US disclosed
US-20070247576-A1 Retardation film, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2007-10-25 US disclosed
US-7205083-B2 Recording material FUJIFILM CORPORATION (JP) 2007-04-17 US disclosed
US-20070048459-A1 Polarizing plate and liquid crystal display apparatus using the same KONICA MINOLTA OPTO, INC. 2007-03-01 US disclosed
US-20070022798-A1 Method of treating optical film, apparatus of treating optical film, and method of manufacturing optical film KONICA MINOLTA OPTO, INC. (JP) 2007-02-01 US disclosed
US-20070009676-A1 Retardation film, polarizing plate, and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2007-01-11 US disclosed
US-20040082472-A1 Recording material FUJI PHOTO FILM CO., LTD. 2004-04-29 US disclosed
US-4735959-A HYPOGLYCEMIC AGENTS DR. KARL THOMAE GMBH (DE) 1988-04-05 US disclosed
US-4567275-A 2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)GLYOXYLIC ACID FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-01-28 US disclosed
EP-0139917-A1 Pharmaceutical preparations, acylated hydrazine derivatives, methods for their preparation CIBA-GEIGY AG (CH) 1985-05-08 EP disclosed
EP-0013762-B1 CEPHEM AND CEPHAM COMPOUNDS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-03-13 EP disclosed
US-4468515-A CEPRALOSPORINS, MICROBIOCIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-08-28 US disclosed
EP-0016565-B1 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLAXO GROUP LIMITED (GB) 1984-05-23 EP disclosed
US-4425340-A ANTIBIOTICS, BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-01-10 US disclosed
US-4390534-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-06-28 US disclosed
US-4381299-A 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-04-26 US disclosed
EP-0064582-A1 Starting compounds for preparing cephem compounds and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-11-17 EP disclosed
US-4332798-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-06-01 US disclosed
US-4331665-A ANTIBIOTICS, BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-05-25 US disclosed
EP-0013762-A2 Cephem and cepham compounds, processes for their preparation, pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-08-06 EP disclosed