SCHEMBL5144346

SCHEMBL5144346

O=c1ccn([C@]2(F)O[C@H](CO)[C@@H](O)[C@]2(O)F)c(=O)[nH]1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.45
SLC28A2 O43868 1/20 0.45
SLC29A1 Q99808 1/20 0.45
SLC28A3 Q9HAS3 1/20 0.45
P2RY14 Q15391 2/20 0.36
CRBN Q96SW2 1/20 0.34
P2RY6 Q15077 6/20 0.34
P2RY2 P41231 1/20 0.34
P2RY4 P51582 1/20 0.34
POLA1 P09884 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27979205 0.89 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL17099404 0.88 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL151327 0.84 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL8579994 0.83 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL6515764 0.81 SLC28A1 (0.38) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL30480815 0.80 SLC28A1 (0.37) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL30974580 0.80 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5075381 0.80 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL25425585 0.79 SLC29A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL27818952 0.79 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250383350-A1 ANALYTE DETECTION USING APTAMERS UNIV MICHIGAN REGENTS (US) 2025-12-18 US disclosed
WO-2025096203-A1 TARGETING A CHIMERIC RNA FOR TREATING CANCER UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-05-08 WO disclosed
CN-114404581-A Cancer vaccine 摩登纳特斯有限公司 2022-04-29 CN disclosed
CN-113577019-A Ready-to-fill gemcitabine solutions 太阳医药工业有限公司 2021-11-02 CN disclosed
EP-2656848-B2 Ready to be infused gemcitabine solution SUN PHARMACEUTICAL IND LTD (IN) 2018-09-19 EP disclosed
US-9241948-B2 Ready to be infused gemcetabine solution SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) 2016-01-26 US disclosed
EP-2656848-B1 Ready to be infused gemcitabine solution SUN PHARMACEUTICAL IND LTD (IN) 2015-04-08 EP disclosed
WO-2013171763-A1 READY TO BE INFUSED GEMCITABINE SOLUTION SUN PHARMACEUTICAL INDUSTRIES LTD (IN) 2013-11-21 WO disclosed
US-20130288994-A1 READY TO BE INFUSED GEMCETABINE SOLUTION SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) 2013-10-31 US disclosed
EP-2656848-A1 Ready to be infused gemcitabine solution Sun Pharmaceutical Industries Limited (IN) 2013-10-30 EP disclosed
EP-1480982-A4 MODIFIED FLUORINATED NUCLEOSIDE ANALOGUES PHARMASSET INC (US) 2007-08-01 EP disclosed
US-20040248844-A1 Method for the treatment or prevention of Flavivirus infections using nucleoside analogues ISMAILI HICHAM MOULAY ALAOUI (CA) 2004-12-09 US disclosed
EP-1480982-A2 MODIFIED FLUORINATED NUCLEOSIDE ANALOGUES Pharmasset Ltd. (BB) 2004-12-01 EP disclosed
US-6784161-B2 VIRICIDES FOR HEPATITIS C BIOCHEM PHARMA, INC. (CA) 2004-08-31 US disclosed
WO-2003068162-A2 MODIFIED FLUORINATED NUCLEOSIDE ANALOGUES PHARMASSET LTD. (BB) 2003-08-21 WO disclosed
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues VIROCHEM PHARMA INC. (CA) 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040248844-A1 Method for the treatment or prevention of Flavivirus infections using nucleoside analogues NUDT1, HAVCR2, SLC28A1 SLC28A1 3/4885SLC28A2 8/4885SLC29A1 7/4885
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues NUDT1, HAVCR2, SLC28A1 SLC28A1 3/4885SLC28A2 8/4885SLC29A1 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.