Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 11/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | L3MBTL3 | Q96JM7 | 12/20 | 0.64 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.62 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.62 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13024627 | 0.87 | L3MBTL1 (0.81) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1735171 | 0.87 | L3MBTL1 (0.81) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31334408 | 0.85 | HPGD (0.76) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3355334 | 0.84 | HPGD (0.80) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL18867940 | 0.84 | HPGD (0.80) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL517817 | 0.82 | HPGD (0.77) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL643480 | 0.82 | ALDH1A1 (0.69) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5337680 | 0.80 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1735976 | 0.80 | L3MBTL1 (0.70) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1735966 | 0.80 | L3MBTL1 (0.70) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136668-A9 | N-BENZOYL-AND N-BENZYLPYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH CORP (US) | 2008-03-27 | — | — | WO | disclosed |