Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144506 | 1.00 | CA2 (0.51) | CA2ALDH1A1SLC7A5LCKPTGS2 | |
| SCHEMBL15105379 | 1.00 | CA2 (0.51) | CA2ALDH1A1SLC7A5LCKPTGS2 | |
| SCHEMBL30611537 | 1.00 | CA2 (0.51) | CA2ALDH1A1SLC7A5LCKPTGS2 | |
| Hydrochloric Acid SCHEMBL7036906 | 0.99 | ALDH1A1 (0.53) | CA2ALDH1A1SLC7A5LCKPTGS2 | |
| Hydrochloric Acid SCHEMBL7036902 | 0.99 | ALDH1A1 (0.53) | CA2ALDH1A1SLC7A5LCKPTGS2 | |
| SCHEMBL3750842 | 0.88 | PNMT (0.56) | ALDH1A1SLC7A5PTGS2 | |
| SCHEMBL3750165 | 0.88 | PNMT (0.56) | ALDH1A1SLC7A5PTGS2 | |
| SCHEMBL3751585 | 0.88 | PNMT (0.56) | ALDH1A1SLC7A5PTGS2 | |
| SCHEMBL5146262 | 0.87 | SLC7A5 (0.48) | CA2ALDH1A1SLC7A5LCKPTGS2 | |
| Hydrochloric Acid SCHEMBL3750170 | 0.87 | ALDH1A1 (0.55) | ALDH1A1SLC7A5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3655036-B1 | COMPOSITIONS FOR TREATING STRESS-RELATED DISORDERS | HOFFMAN TECH LLC (US) | 2024-09-04 | — | — | EP | claimed |
| CN-116783212-A | Compositions and methods for modulating cancer in non-human mammals | 霍夫曼技术有限责任公司 | 2023-09-19 | — | — | CN | claimed |
| CN-114901272-A | Sustained release preparation | 霍夫曼技术有限责任公司 | 2022-08-12 | — | — | CN | claimed |
| EP-3060200-B1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | TYME INC (US) | 2021-05-26 | — | — | EP | claimed |
| CN-109195601-A | Pharmaceutical composition for treating cancer | 迪美公司 | 2019-01-11 | — | — | CN | claimed |
| CN-116783212-A | Compositions and methods for modulating cancer in non-human mammals | 霍夫曼技术有限责任公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-111032089-A | Compositions for treating stress-related disorders | 霍夫曼技术公司 | 2020-04-17 | — | — | CN | disclosed |
| EP-1540341-A4 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIV ROCHESTER MEDICAL CT (US) | 2007-01-10 | — | — | EP | disclosed |
| US-20060166295-A1 | Method for determination of likelihood of occurrence of preterm labor in pregnant females | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-07-27 | — | — | US | disclosed |
| EP-1540341-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | The University of Rochester Medical Center (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004003555-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) | 2004-01-08 | — | — | WO | disclosed |