Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007764 | 0.83 | SLC6A2 (0.37) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL6540298 | 0.81 | SLC6A2 (0.36) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL6336901 | 0.81 | SLC6A2 (0.36) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL6541046 | 0.81 | SLC6A2 (0.36) | SLC6A4SLC6A2 | |
| SCHEMBL16757084 | 0.75 | SLC6A2 (0.45) | SLC6A4SLC6A2 | |
| SCHEMBL11276420 | 0.72 | PNMT (0.50) | SLC6A4HTR2CHTR2BHTR2AACP3 | |
| SCHEMBL11722793 | 0.72 | HTR1A (0.57) | HTR2CHTR2BHTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL19385651 | 0.71 | HTR2C (0.57) | HTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL6463706 | 0.71 | SLC6A2 (0.40) | SLC6A4HTR2CHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL11275846 | 0.71 | PNMT (0.49) | SLC6A4HTR2CHTR2BHTR2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004289-A1 | Glycine transporter-1 inhibitors | AMGEN INC. | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004289-A1 | Glycine transporter-1 inhibitors | SLC18A2, SLC7A11, SLC6A5 | SLC6A4 16/4885HTR2C 587/4885HTR2B 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.