Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21679889 | 0.91 | HNF4A (0.60) | HNF4AHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL20503723 | 0.91 | HNF4A (0.60) | HNF4AHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL27178395 | 0.89 | HNF4A (0.63) | HNF4AHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL27178358 | 0.83 | HNF4A (0.62) | HNF4AHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL27178330 | 0.83 | HNF4A (0.58) | HNF4AHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL28811895 | 0.83 | HNF4A (0.49) | HNF4AHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL29861585 | 0.83 | HNF4A (0.49) | HNF4AHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL542005 | 0.83 | HNF4A (0.73) | HNF4AHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL15524796 | 0.83 | ALDH1A1 (0.55) | HNF4AHSD17B10ALDH1A1TDP1POLB | |
| SCHEMBL10411995 | 0.82 | TSHR (0.57) | HNF4AHSD17B10ALDH1A1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287705-A1 | METHOD OF PRODUCING ETHYNYL COMPOUND, METHOD OF HANDLING ETHYNYL COMPOUND, AND METHOD OF USING ASCORBIC ACID OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287705-A1 | METHOD OF PRODUCING ETHYNYL COMPOUND, METHOD OF HANDLING ETHYNYL COMPOUND, AND METHOD OF USING ASCORBIC ACID OR SALT THEREOF | KEAP1, CBR1, PROC | HNF4A 4268/4885HSD17B10 204/4885CDC25A 3288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.