SCHEMBL514483

SCHEMBL514483

CSc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.56
ACHE P22303 1/20 0.56
MAPK1 P28482 4/20 0.55
KDM4E B2RXH2 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 1/20 0.55
NR2F2 P24468 1/20 0.55
RAB9A P51151 1/20 0.55
MAPT P10636 5/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
GSK3B P49841 1/20 0.53
FBP1 P09467 1/20 0.52
ALDH1A1 P00352 7/20 0.50
RECQL P46063 1/20 0.50
CDK2 P24941 1/20 0.50
LMNA P02545 1/20 0.48
NOS3 P29474 2/20 0.47
NOS1 P29475 2/20 0.47
CES1 P23141 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11453922 0.94 MAPT (0.66) HSD17B10ACHEMAPK1KDM4ESMN1; SMN2
SCHEMBL620493 0.88 HSPB1 (0.59) HSD17B10ACHEMAPK1KDM4ESMN1; SMN2
SCHEMBL10420571 0.88 CASP3 (0.50) HSD17B10ACHEMAPK1KDM4ESMN1; SMN2
SCHEMBL9159620 0.82 SMN1; SMN2 (0.53) MAPK1KDM4ESMN1; SMN2NPC1NR2F2
SCHEMBL14031111 0.82 GAA (0.59) HSD17B10MAPK1KDM4ESMN1; SMN2NPC1
SCHEMBL4908007 0.82 HSD17B10 (0.52) HSD17B10ACHEMAPK1KDM4ESMN1; SMN2
SCHEMBL3671853 0.81 HSPB1 (0.51) MAPK1KDM4ESMN1; SMN2NPC1NR2F2
SCHEMBL3328543 0.80 MAPT (0.79) HSD17B10ACHEMAPK1KDM4ESMN1; SMN2
SCHEMBL223594 0.80 MEN1 (0.59) HSD17B10ACHEMAPK1MAPTMEN1
SCHEMBL4163474 0.80 MAPT (0.79) HSD17B10ACHEMAPK1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024239574-A1 CARBON-COATED NICKEL-PALLADIUM ALLOY NANOPARTICLE COMPOSITE MATERIAL, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国石油化工股份有限公司 2024-11-28 WO claimed
WO-2023027630-A9 A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-07-27 WO claimed
WO-2023027630-A2 A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-03-02 WO claimed
CN-114773240-A Method for preparing p-nitrobenzenesulfide by using microchannel 江苏永创医药科技股份有限公司 2022-07-22 CN claimed
CN-106622385-A Double-core magnesium-germanium tungsten oxide cluster catalyst and preparing method and application thereof 聊城大学 2017-05-10 CN claimed
US-7732534-B2 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2010-06-08 US claimed
US-20080051552-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION 2008-02-28 US claimed
US-20080051519-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2008-02-28 US claimed
EP-1304325-A1 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-04-23 EP claimed
US-5808164-A Process for producing aromatic sulfides PHILLIPE PETROLEUM COMPANY (US) 1998-09-15 US claimed
US-5618981-A Process for producing aromatic sulfides PHILLIPS PETROLEUM COMPANY (US) 1997-04-08 US claimed
US-4298761-A Preparation of 4-nitrothioanisole BAYER AKTIENGESELLSCHAFT (DE) 1981-11-03 US claimed
EP-0014368-B1 PROCESS FOR THE PREPARATION OF 4-NITROTHIOANISOL BAYER AG (DE) 1981-07-22 EP claimed
US-4267340-A BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-12 US claimed
EP-0014368-A1 Process for the preparation of 4-nitrothioanisol BAYER AG (DE) 1980-08-20 EP claimed
US-4092474-A Cephalosporins having a metaloxy group in 3-substituent SHIONOGI & CO., LTD. (JA) 1978-05-30 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
EP-4713096-A1 CDK INHIBITOR COMPOUNDS Aleksia Therapeutics, Inc. (US) 2026-03-25 EP disclosed
US-4159984-A METAL AND PROTON DONOR SHIONOGI & CO., LTD. (JP) 1979-07-03 US disclosed
US-4092474-A Cephalosporins having a metaloxy group in 3-substituent SHIONOGI & CO., LTD. (JA) 1978-05-30 US disclosed