Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842471 | 0.84 | HTR2A (0.33) | PDE10A | |
| SCHEMBL5146698 | 0.83 | MBOAT4 (0.32) | PDE10A | |
| Hydrochloric Acid SCHEMBL1231715 | 0.83 | HTR2A (0.32) | PDE10A | |
| Hydrochloric Acid SCHEMBL1842432 | 0.83 | HTR2A (0.32) | PDE10A | |
| SCHEMBL5145218 | 0.76 | HTR6 (0.40) | — | |
| SCHEMBL13016503 | 0.73 | APOBEC3A (0.33) | PDE10A | |
| SCHEMBL10118586 | 0.72 | HTR6 (0.33) | PDE10A | |
| SCHEMBL1842587 | 0.69 | ALDH1A1 (0.33) | PDE10A | |
| Hydrochloric Acid SCHEMBL1839700 | 0.69 | ALDH1A1 (0.34) | PDE10A | |
| SCHEMBL12659353 | 0.68 | CCNA2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | claimed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| EP-1792606-B1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | OREAL (FR) | 2011-05-18 | — | — | EP | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | KRT18, MARK1, MARK2 | PDE10A 1900/4885DHODH 893/4885 |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | KRT18, MARK1, MARK2 | PDE10A 1990/4885DHODH 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.