Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diphenylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL11870143 | 0.95 | HSD17B10 (0.63) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| Diphenylamine SCHEMBL28157736 | 0.95 | HSD17B10 (0.63) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| SCHEMBL4443489 | 0.86 | ALDH1A1 (0.56) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| SCHEMBL540370 | 0.81 | ALDH1A1 (0.56) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| Diphenylamine SCHEMBL1008717 | 0.81 | HSD17B10 (0.67) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| Diphenylamine SCHEMBL1008716 | 0.81 | HSD17B10 (0.67) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| Diphenylamine SCHEMBL28015233 | 0.81 | HSD17B10 (0.67) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| Sulfuric Acid SCHEMBL2959599 | 0.80 | ALDH1A1 (0.48) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| Diphenylamine SCHEMBL1619083 | 0.80 | HSD17B10 (1.00) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR | |
| Diphenylamine SCHEMBL3003404 | 0.80 | HSD17B10 (1.00) | HSD17B10ALDH1A1ALOX12L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667827-A4 | PROCESS FOR THE TREATMENT OF WOOD | UNIV MELBOURNE (AU) | 2007-11-28 | — | — | EP | disclosed |
| US-20070056655-A1 | Process for the treatment of wood | UNIVERSITY OF MELBOURNE (AU) | 2007-03-15 | — | — | US | disclosed |
| EP-1667827-A1 | PROCESS FOR THE TREATMENT OF WOOD | THE UNIVERSITY OF MELBOURNE (AU) | 2006-06-14 | — | — | EP | disclosed |
| WO-2004113039-A1 | PROCESS FOR THE TREATMENT OF WOOD | THE UNIVERSITY OF MELBOURNE (AU) | 2004-12-29 | — | — | WO | disclosed |
| US-5099006-A | ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates | RHONE-POULENC INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-4800072-A | Anhydrous cerous nitrate-ammonium nitrate complex and a process for its preparation from ceric ammonium nitrate | RHONE POULENC, INC. (US) | 1989-01-24 | — | — | US | disclosed |