Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12660106 | 0.84 | POLB (0.51) | POLBCTDSP1TDP1KMT2AALDH1A1 | |
| SCHEMBL16081490 | 0.79 | PDE1A (0.34) | POLBKMT2AALDH1A1KDM4EHTT | |
| SCHEMBL17851627 | 0.78 | POLB (0.39) | POLBCTDSP1TDP1KMT2AALDH1A1 | |
| SCHEMBL26096935 | 0.78 | POLB (0.39) | POLBCTDSP1TDP1KMT2AALDH1A1 | |
| SCHEMBL3851033 | 0.77 | — | — | |
| SCHEMBL17365402 | 0.77 | CYP2C9 (0.34) | TDP1ALDH1A1KDM4EHTT | |
| SCHEMBL9957804 | 0.77 | LMNA (0.37) | — | |
| SCHEMBL15291896 | 0.77 | TDP1 (0.44) | TDP1ALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL3853545 | 0.76 | CHRNB2 (0.35) | — | |
| SCHEMBL5143428 | 0.76 | MEN1 (0.34) | TDP1KMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | claimed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | KRT18, MARK1, MARK2 | POLB 1512/4885CTDSP1 1982/4885TDP1 1423/4885 |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | KRT18, MARK1, MARK2 | POLB 1554/4885CTDSP1 1906/4885TDP1 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.