SCHEMBL5145353

SCHEMBL5145353

Cc1ccc(S(=O)(=O)OC(C)Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CNR2 P34972 1/20 0.46
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
FFAR1 O14842 1/20 0.43
VDR P11473 1/20 0.43
TDP1 Q9NUW8 3/20 0.40
CA12 O43570 2/20 0.40
CA9 Q16790 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
DHODH Q02127 1/20 0.39
GAA P10253 3/20 0.39
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7106921 0.90 CYP1A2 (0.44) HTTSMN1; SMN2ALDH1A1KMT2ATDP1
SCHEMBL10688193 0.84 ENPP3 (0.46) SMN1; SMN2CNR2ALDH1A1MEN1KMT2A
SCHEMBL890642 0.82 GAA (0.50) HTTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL5384073 0.82 HTT (0.60) HTTSMN1; SMN2CNR2ALDH1A1MEN1
SCHEMBL14366359 0.82 HTT (0.60) HTTSMN1; SMN2CNR2ALDH1A1MEN1
SCHEMBL5384070 0.82 HTT (0.60) HTTSMN1; SMN2CNR2ALDH1A1MEN1
SCHEMBL10905307 0.81 ACHE (0.50) HTTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL10663899 0.79 KMT2A (0.41) HTTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL9767627 0.79 GAA (0.46) HTTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL8571194 0.79 HTT (0.45) HTTSMN1; SMN2CNR2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 US disclosed
US-20070004923-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed
US-20040063962-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2004-04-01 US disclosed
US-6667405-B2 Nitrogen containing heterocyclilc compound and quaternary salt compound which are raw material of the methine dye, useful as coloring agent, a light absorber, for an optical disc or marker for diagnosis FUJI PHOTO FILM CO., LTD. (JP) 2003-12-23 US disclosed
US-20020076666-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2002-06-20 US disclosed
US-6333146-B1 METHINE DYE WHICH IS USEFUL AS A COLORING AGENT, A LIGHT ABSORBER, A DYE FOR AN OPTICAL DISC, SPECTRAL SENSITIZING DYES FOR A SILVER HALIDE PHOTOGRAPH, AN ELECTROPHOTOGRAPH AND A PHOTOELECTRIC CONVERSION DEVICE, OR A MARKER FOR DIAGNOSIS FUJI PHOTO FILM CO., LTD. (JP) 2001-12-25 US disclosed
EP-0716135-B1 MARKING COMPOSITION AND LASER MARKING METHOD NIPPON KAYAKU KK (JP) 1999-09-29 EP disclosed
US-5824715-A ULTRAVIOLET RAY CURING RESIN, PHOTOINITIATOR, LEUCO DYE, COLOR DEVELOPER; USED TO MARK SURFACE OF MOLDED ARTICLE BY LASER BEAM IRRADIATION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-10-20 US disclosed
EP-0716135-A1 MARKING COMPOSITION AND LASER MARKING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1996-06-12 EP disclosed
US-4596997-A Phenolic compound, preparation thereof and recording material employing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-06-24 US disclosed
US-3980678-A Anthraquinone disperse dyes SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004923-A1 Methine compound and silver halide photographic material containing the same PYM1, NPM1, METTL3 HTT 295/4885SMN1; SMN2 2114/4885CNR2 2213/4885
US-20020076666-A1 Methine compound and silver halide photographic material containing the same PYM1, NPM1, METTL3 HTT 365/4885SMN1; SMN2 2331/4885CNR2 2996/4885
US-20040063962-A1 Methine compound and silver halide photographic material containing the same PYM1, NPM1, METTL3 HTT 361/4885SMN1; SMN2 2330/4885CNR2 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.