Triethylene Glycol

Triethylene Glycol

SCHEMBL5145504

C=C.C=C.CCOCC.OCCOCCOCCO

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
TSHR P16473 3/20 0.56
MAPK1 P28482 2/20 0.56
THRB P10828 2/20 0.52
HTT P42858 1/20 0.52
MAPT P10636 1/20 0.52
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
CASP1 P29466 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SLCO1B3 Q9NPD5 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
APP P05067 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL5335679 1.00 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ATSHRMAPK1
Di(Hydroxyethyl)Ether SCHEMBL414706 0.97 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ATSHRMAPK1
Di(Hydroxyethyl)Ether SCHEMBL4017515 0.97 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ATSHRMAPK1
Diethylene Glycol Monoethyl Ether SCHEMBL1618672 0.94 ALDH1A1 (0.78) ALDH1A1MEN1KMT2ATSHRMAPK1
Diethylene Glycol Monoethyl Ether SCHEMBL10882772 0.94 ALDH1A1 (0.78) ALDH1A1MEN1KMT2ATSHRMAPK1
Ethylene SCHEMBL28794602 0.94 ALDH1A1 (0.78) ALDH1A1MEN1KMT2ATSHRMAPK1
Triethylene Glycol SCHEMBL55649 0.94 ALDH1A1 (0.77) ALDH1A1MEN1KMT2ATSHRMAPK1
Tetraethylene Glycol SCHEMBL216925 0.94 ALDH1A1 (0.77) ALDH1A1MEN1KMT2ATSHRMAPK1
Triethylene Glycol SCHEMBL18546565 0.94 ALDH1A1 (0.77) ALDH1A1MEN1KMT2ATSHRMAPK1
Triethylene Glycol SCHEMBL15525927 0.94 ALDH1A1 (0.77) ALDH1A1MEN1KMT2ATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7235673-B2 Glycolide production process, and glycolic acid oligomer for glycolide production KUREHA CORPORATION (JP) 2007-06-26 US disclosed
EP-1366037-B1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA CHEMICAL IND CO LTD (JP) 2005-08-24 EP disclosed
US-6891048-B2 Glycolide production process, and glycolic acid composition KUREHA KAGAKU KOGYO KK (JP) 2005-05-10 US disclosed
EP-1377566-B1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION KUREHA CHEMICAL IND CO LTD (JP) 2004-09-22 EP disclosed
US-20040122240-A1 Glycolide production process, and glycolic acid oligomer for glycolide production KUREHA CORPORATION (JP) 2004-06-24 US disclosed
US-20040087805-A1 Glycolide production process, and glycolic acid composition KUREHA CORPORATION (JP) 2004-05-06 US disclosed
EP-1377566-A1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION Kureha Chemical Industry Co., Ltd. (JP) 2004-01-07 EP disclosed
EP-1366037-A2 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-12-03 EP disclosed
WO-2002083661-A1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION KUREHA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 2002-10-24 WO disclosed
WO-2002070508-A2 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA KAGAKU KOGYO K.K. (JP) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087805-A1 Glycolide production process, and glycolic acid composition DDOST, DAD1, AGL ALDH1A1 3923/4885MEN1 4085/4885KMT2A 4398/4885
US-20040122240-A1 Glycolide production process, and glycolic acid oligomer for glycolide production UGCG, DAD1, DDOST ALDH1A1 1400/4885MEN1 4170/4885KMT2A 4761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.