Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.88 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.78 |
| ▸ | CA12 | O43570 | 3/20 | 0.78 |
| ▸ | CA1 | P00915 | 3/20 | 0.78 |
| ▸ | CA2 | P00918 | 3/20 | 0.78 |
| ▸ | CA3 | P07451 | 3/20 | 0.78 |
| ▸ | CA4 | P22748 | 3/20 | 0.78 |
| ▸ | CA6 | P23280 | 3/20 | 0.78 |
| ▸ | CA5A | P35218 | 3/20 | 0.78 |
| ▸ | CA7 | P43166 | 3/20 | 0.78 |
| ▸ | CA9 | Q16790 | 3/20 | 0.78 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.78 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.78 |
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Putrescine SCHEMBL7599194 | 0.94 | NFKB1 (0.78) | NFKB1DNM1CA12CA1CA2 | |
| SCHEMBL5718543 | 0.94 | DNM1 (0.89) | NFKB1DNM1CA12CA1CA2 | |
| SCHEMBL29160873 | 0.94 | DNM1 (0.89) | NFKB1DNM1CA12CA1CA2 | |
| Putrescine SCHEMBL21642 | 0.94 | — | — | |
| SCHEMBL7267804 | 0.94 | NFKB1 (0.75) | NFKB1DNM1CA12CA1CA2 | |
| SCHEMBL16345592 | 0.94 | NFKB1 (0.75) | NFKB1DNM1CA12CA1CA2 | |
| Putrescine SCHEMBL160836 | 0.94 | NFKB1 (1.00) | NFKB1DNM1CA12CA1CA2 | |
| SCHEMBL8182 | 0.94 | — | — | |
| SCHEMBL25350595 | 0.88 | — | — | |
| Putrescine SCHEMBL22227753 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070006775-A1 | Method for producing a wet-laid fiber mat | OWENS CORNING INTELLECTUAL CAPITAL, LLC | 2007-01-11 | — | — | US | claimed |
| EP-0315027-A2 | Amide-ester block copolymers and process for the preparation thereof | GENERAL ELECTRIC COMPANY (US) | 1989-05-10 | — | — | EP | claimed |
| US-20240199648-A1 | MAP4K1 INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2024-06-20 | — | — | US | disclosed |
| EP-4305041-A1 | MAP4K1 INHIBITORS | Blueprint Medicines Corporation (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-117295748-A | MAP4K1 inhibitors | 缆图药品公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114477206-B | Modification method of Ti-containing heteroatom molecular sieve | 中国石油化工股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| WO-2022192145-A1 | MAP4K1 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2022-09-15 | — | — | WO | disclosed |
| EP-3157978-B1 | STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS | SYMO CHEM B V (NL) | 2021-08-11 | — | — | EP | disclosed |
| CN-112840021-A | Compounds for stabilizing hydrolases in liquids | 巴斯夫欧洲公司 | 2021-05-25 | — | — | CN | disclosed |
| US-10556994-B2 | Strictly segmented thermoplastic elastomers as biodegradable biomaterials | SYMO-CHEM B.V. (NL) | 2020-02-11 | — | — | US | disclosed |
| US-20180334543-A1 | STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS | SYMO-CHEM B.V. (NL) | 2018-11-22 | — | — | US | disclosed |
| EP-0469331-A1 | Process for preparing organic esters and amides and catalyst system therefor | MONTELL NORTH AMERICA INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| EP-0468289-A2 | Profiled emulsion polymers, especially for water and aqueous solution developable, photopolymerizable recording material | BASF Aktiengesellschaft (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-4810436-A | PREPARED FROM DECABORANE AND AN AMINE OR PHOSPHINE | HOECHST CELANESE CORP. (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0231002-A2 | Crosslinkable solid rubbery polymers | BASF Aktiengesellschaft (DE) | 1987-08-05 | — | — | EP | disclosed |
| US-4578284-A | FROM DIMER ACID | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1986-03-25 | — | — | US | disclosed |
| US-4271284-A | Process for the production of poly(amine allyl halide halohydrin silicate) copolymer and their reaction products | BLOUNT DAVID H | 1981-06-02 | — | — | US | disclosed |
| US-4235686-A | POLYURETHANE, UNSATURATED POLYESTER, AND ETHYLENICALLY UNSATURATED MONOMER | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-11-25 | — | — | US | disclosed |
| US-4205155-A | Process for the production of poly(allyl halide amine silicate) reaction products | BLOUNT DAVID H | 1980-05-27 | — | — | US | disclosed |
| US-4157438-A | Process for the production of poly(amine allyl halide) copolymer and their reaction products | BLOUNT DAVID H | 1979-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199648-A1 | MAP4K1 INHIBITORS | MAP4K1, MAP4K4, MAP4K2 | NFKB1 515/4885DNM1 2516/4885CA12 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.