Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | DRD4 | P21917 | 5/20 | 0.53 |
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253804 | 0.96 | KCNA3 (0.67) | KCNA3DRD2DRD4DRD3HDAC3 | |
| SCHEMBL7027136 | 0.94 | KCNA3 (0.64) | KCNA3DRD2DRD4DRD3HDAC3 | |
| SCHEMBL5254257 | 0.94 | KCNA3 (0.64) | KCNA3DRD2DRD4DRD3HDAC3 | |
| SCHEMBL1231287 | 0.89 | KCNA3 (0.56) | KCNA3DRD2DRD4DRD3HDAC3 | |
| SCHEMBL27975023 | 0.84 | LTA4H (0.65) | KCNA3DRD2DRD3ALDH1A1LTA4H | |
| SCHEMBL9908990 | 0.84 | KCNA3 (0.50) | KCNA3DRD2DRD4DRD3TAAR1 | |
| SCHEMBL1025 | 0.82 | KCNA3 (0.88) | KCNA3DRD2DRD4DRD3HDAC3 | |
| SCHEMBL6394914 | 0.80 | DRD2 (0.49) | DRD2DRD4DRD3ALDH1A1L3MBTL1 | |
| SCHEMBL16442726 | 0.80 | DRD2 (0.56) | DRD2DRD4DRD3ALDH1A1L3MBTL1 | |
| Ethoxycarbonyl Group SCHEMBL27277943 | 0.80 | LTA4H (0.62) | KCNA3DRD2DRD3ALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152759-B1 | AMINOISOTHIAZOLE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1989-08-23 | — | — | EP | claimed |
| EP-0150034-B1 | DERIVATIVES OF 2-AMINOTHIOPHENE | BASF Aktiengesellschaft (DE) | 1989-08-02 | — | — | EP | claimed |
| US-4785116-A | Aminoisothiazole compounds | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | claimed |
| US-20210309619-A1 | ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-10-07 | — | — | US | disclosed |
| US-11109593-B2 | Isoxazolin-5-one derivative and herbicide containing same as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-09-07 | — | — | US | disclosed |
| EP-3828176-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-20200267985-A1 | ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| WO-2020022350-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | 北興化学工業株式会社 | 2020-01-30 | — | — | WO | disclosed |
| EP-1221440-B1 | Benzoheterocyclic derivatives useful as vasopressin or oxytocin modulators | OTSUKA PHARMA CO LTD (JP) | 2007-04-25 | — | — | EP | disclosed |
| US-7205083-B2 | Recording material | FUJIFILM CORPORATION (JP) | 2007-04-17 | — | — | US | disclosed |
| US-6787502-B2 | INCLUSION OF A STRONGLY BASIC BIS-GUANIDINE COMPOUND THAT IS SUPERIOR IN DIFFUSION RESISTANCE; SPECIFIED DIAZONIUM SALT COMPOUND AND A PYRROLO(1,2-A)PYRIMIDINE COUPLER IN RECORDING LAYER | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| WO-1996003462-A1 | AZO DYES HAVING A COUPLING COMPONENT FROM THE AMINOTHIAZOLE SERIES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |
| WO-1995034540-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-12-21 | — | — | WO | disclosed |
| EP-0152759-B1 | AMINOISOTHIAZOLE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1989-08-23 | — | — | EP | disclosed |
| EP-0150034-B1 | DERIVATIVES OF 2-AMINOTHIOPHENE | BASF Aktiengesellschaft (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4785116-A | Aminoisothiazole compounds | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0152759-A1 | Aminoisothiazole compounds | BASF Aktiengesellschaft (DE) | 1985-08-28 | — | — | EP | disclosed |
| EP-0150034-A2 | Derivatives of 2-aminothiophene | BASF Aktiengesellschaft (DE) | 1985-07-31 | — | — | EP | disclosed |
| EP-0150034-A2 | Derivatives of 2-aminothiophene | BASF Aktiengesellschaft (DE) | 1985-07-31 | — | — | EP | disclosed |
| EP-0000644-A2 | Lower cycloalkyl substituted-benzene derivatives, the preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200267985-A1 | ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HAX1, CYP4X1, CANX | KCNA3 641/4885DRD2 2094/4885DRD4 1093/4885 |
| US-11109593-B2 | Isoxazolin-5-one derivative and herbicide containing same as active ingredient | HAX1, CYP4X1, CANX | KCNA3 641/4885DRD2 2094/4885DRD4 1093/4885 |
| US-20210309619-A1 | ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | HAX1, CYP4X1, CNPY2 | KCNA3 385/4885DRD2 1922/4885DRD4 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.