SCHEMBL5145695

SCHEMBL5145695

CC(C)(CCC(=O)O)CCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.59
FFAR1 O14842 7/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
HDAC3 O15379 1/20 0.55
MAPK1 P28482 1/20 0.55
ADRA1A P35348 1/20 0.55
HDAC4 P56524 1/20 0.55
SLC6A3 Q01959 1/20 0.55
HDAC1 Q13547 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC9 Q9UKV0 1/20 0.55
HDAC5 Q9UQL6 1/20 0.55
MAPT P10636 2/20 0.52
RXFP1 Q9HBX9 1/20 0.52
ALDH1A1 P00352 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5750633 0.83 KEAP1 (0.50) KEAP1FFAR1HDAC2HDAC8HDAC6
SCHEMBL7450180 0.83 SLC13A5 (0.50) KEAP1FFAR1HDAC2HDAC8HDAC6
SCHEMBL29200276 0.82 TDP1 (0.45) KEAP1FFAR1HDAC2HDAC8HDAC6
SCHEMBL5517732 0.81 HSD17B10 (0.51) KEAP1FFAR1HDAC2HDAC8HDAC6
SCHEMBL29200283 0.80 ALOX5 (0.52) SMN1; SMN2MAPTL3MBTL1POLBTDP1
SCHEMBL29200278 0.80 ALDH1A1 (0.51) MAPK1SLC6A3SMN1; SMN2ALDH1A1KMT2A
SCHEMBL23369879 0.79 ALDH1A1 (0.52) KEAP1FFAR1HDAC2HDAC8HDAC6
SCHEMBL6989028 0.79 TDP1 (0.54) KEAP1MAPK1MAPTALDH1A1MEN1
SCHEMBL11529406 0.77 NAALAD2 (0.50) FFAR1HDAC2HDAC8HDAC3ADRA1A
Phenyl Propionic Acid SCHEMBL9001639 0.76 KEAP1 (0.83) KEAP1FFAR1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689848-B Fragrance composition 奇华顿股份有限公司 2022-12-23 CN disclosed
US-20150216182-A1 COMPOSITIONS AND METHODS OF THE ATTRACTION AND REPULSION OF INSECTS OLFACTOR LABORATORIES, INC. 2015-08-06 US disclosed
US-20070088508-A1 Cocrystallization methods APTUIT (WEST LAFAYETTE), LLC 2007-04-19 US disclosed
WO-2007038524-A2 COCRYSTALLIZATION METHODS SSCI, INC. (US) 2007-04-05 WO disclosed