SCHEMBL5145772

SCHEMBL5145772

[CH2]CCc1ccc(C=C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.37
HDAC8 Q9BY41 1/20 0.36
POLB P06746 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
THRB P10828 1/20 0.31
TP53 P04637 2/20 0.31
MAPT P10636 2/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GFER P55789 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50012 0.87 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL1647493 0.87 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL703049 0.86 ALDH1A1 (0.50) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL7764480 0.82 ALDH1A1 (0.46) ALDH1A1TSHRTHRBTP53CA1
SCHEMBL16551533 0.82 ALDH1A1 (0.46) ALDH1A1TSHRTHRBTP53CA1
SCHEMBL177912 0.82 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL1140696 0.82 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8THRB
SCHEMBL2745550 0.81 GFER (0.42) ALDH1A1TDP1CA2KMT2AGFER
SCHEMBL594419 0.80 ALDH1A1 (0.55) ALDH1A1TSHRTDP1THRBTP53
SCHEMBL891516 0.80 ALDH1A1 (0.55) ALDH1A1TSHRTDP1HDAC8POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658899-A1 COSMETIC CONTAINING LIQUID ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2013-11-06 EP disclosed
EP-2654713-A1 POLYSILOXANE-HYDROCARBYLENE AMINOHYDROCARBYLENE MULTIBLOCK COPOLYMER AND METHOD FOR PRODUCING THE SAME Dow Corning Toray Co., Ltd. (JP) 2013-10-30 EP disclosed
EP-2655480-A2 POLYSILOXANE-N, N-DIHYDROCARBYLENE SUGAR-MODIFIED MULTIBLOCK COPOLYMER AND METHOD FOR PRODUCING THE SAME Dow Corning Toray Co., Ltd. (JP) 2013-10-30 EP disclosed
EP-2598113-A1 COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2013-06-05 EP disclosed
EP-2563844-A1 ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL -BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME Dow Corning Toray Co., Ltd. (JP) 2013-03-06 EP disclosed
EP-2563845-A1 NOVEL ORGANOPOLYSILOXANE, SURFACTANT, EMULSION COMPOSITION, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL, GELLING AGENT, GEL COMPOSITION, AND COSMETIC RAW MATERIAL COMPRISING NOVEL ORGANOPOLYSILOXANE, AS WELL AS, PREPARATION FOR EXTERNAL USE AND COSMETIC COMPRISING THE SAME Dow Corning Toray Co., Ltd. (JP) 2013-03-06 EP disclosed
CN-102906161-A Novel organopolysiloxane, surfactant, emulsion composition, powder treatment agent, thickening agent of oil-based raw material, gelling agent, gel composition, and cosmetic raw material comprising novel organopolysiloxane, as well as, preparation for external use and cosmetic comprising the same DOW CORNING TORAY CO LTD 2013-01-30 CN disclosed
EP-2516510-A1 SURFACE-TREATMENT AGENT FOR POWDER FOR USE IN COSMETIC AND COSMETIC CONTAINING POWDER TREATED WITH THE SAME Dow Corning Toray Co., Ltd. (JP) 2012-10-31 EP disclosed
EP-0932083-B1 Coating composition for electrifying members and electrophotographic carrier SHINETSU CHEMICAL CO (JP) 2012-09-05 EP disclosed
WO-2012091155-A1 COSMETIC CONTAINING LIQUID ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2012-07-05 WO disclosed
WO-2012086847-A2 POLYSILOXANE-N, N-DIHYDROCARBYLENE SUGAR-MODIFIED MULTIBLOCK COPOLYMER AND METHOD FOR PRODUCING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2012-06-28 WO disclosed
WO-2012086843-A1 POLYSILOXANE-HYDROCARBYLENE AMINOHYDROCARBYLENE MULTIBLOCK COPOLYMER AND METHOD FOR PRODUCING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2012-06-28 WO disclosed
WO-2012015070-A1 COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2012-02-02 WO disclosed
US-7172822-B2 Network conductor and its production method and use FUJI PHOTO FILM CO., LTD. (JP) 2007-02-06 US disclosed
EP-1614715-A1 POLYESTER RESIN COMPOSITION KANEKA CORPORATION (JP) 2006-01-11 EP disclosed
US-20040177982-A1 Image display having electromagnetic shield and method for producing same FUJI PHOTO FILM CO., LTD. 2004-09-16 US disclosed
US-20040150326-A1 Network conductor and its production method and use FUJI PHOTO FILM CO., LTD 2004-08-05 US disclosed
US-6100332-A REACTION PRODUCT OBTAINED BY REACTING SILICONE RESIN WITH RADICAL POLYMERIZABLE VINYL MONOMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-08 US disclosed
EP-0932083-A2 Coating composition for electrifying members and electrophotographic carrier SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-07-28 EP disclosed