Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647493 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL50012 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL891581 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL177912 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL1140696 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8THRB | |
| SCHEMBL6278400 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1THRBTP53 | |
| SCHEMBL5145772 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL3797757 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1THRBTP53 | |
| SCHEMBL594419 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1THRBTP53 | |
| SCHEMBL1140602 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083575-A1 | COMB ARCHITECTURE OLEFIN BLOCK COPOLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-05 | — | — | US | claimed |
| US-7858707-B2 | Catalytic olefin block copolymers via polymerizable shuttling agent | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-12-28 | — | — | US | claimed |
| CN-102443083-B | Comb architecture olefin block copolymers | 陶氏环球技术有限责任公司 | 2018-04-27 | — | — | CN | disclosed |
| EP-2436703-B1 | Comb architecture olefin block copolymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-25 | — | — | EP | disclosed |
| US-8907034-B2 | Comb architecture olefin block copolymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| EP-1940896-B1 | CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-10-22 | — | — | EP | disclosed |
| US-8415434-B2 | Catalytic olefin block copolymers via polymerizable shuttling agent | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120083575-A1 | COMB ARCHITECTURE OLEFIN BLOCK COPOLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-05 | — | — | US | disclosed |
| US-20110092651-A1 | Catalytic Olefin Block Copolymers Via Polymerizable Shuttling Agent | ARRIOLA DANIEL J | 2011-04-21 | — | — | US | disclosed |
| US-7858707-B2 | Catalytic olefin block copolymers via polymerizable shuttling agent | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20090163667-A1 | CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-06-25 | — | — | US | disclosed |
| EP-1940896-A1 | CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT | Dow Global Technologies Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007035492-A1 | CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-03-29 | — | — | WO | disclosed |