SCHEMBL1982897

SCHEMBL1982897

C=C(C)C(=O)[N+](C)(C)C.CCOP(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 1/20 0.37
PPARD Q03181 2/20 0.34
LPAR3 Q9UBY5 5/20 0.33
LPAR1 Q92633 3/20 0.33
LPAR2 Q9HBW0 3/20 0.33
TSHR P16473 2/20 0.33
THRB P10828 1/20 0.32
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
TPI1 P60174 1/20 0.31
LPAR6 P43657 1/20 0.30
LPAR4 Q99677 1/20 0.30
LPAR5 Q9H1C0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27783396 0.80 PPARD (0.39) BTN3A1PPARDLPAR3LPAR1LPAR2
Methacrylic Acid SCHEMBL1877845 0.80 PEPD (0.41) BTN3A1PPARDLPAR3LPAR1LPAR2
SCHEMBL1072477 0.79 THRB (0.37) BTN3A1PPARDLPAR3LPAR1LPAR2
Methacrylic Acid SCHEMBL27796761 0.79 PEPD (0.40) BTN3A1PPARDLPAR3LPAR1LPAR2
SCHEMBL5145800 0.76 THRB (0.42) BTN3A1PPARDLPAR3LPAR1LPAR2
Ethylene SCHEMBL790436 0.75
Ethylene SCHEMBL17060515 0.75 TSHR (0.50) PPARDLPAR3LPAR1LPAR2TSHR
SCHEMBL40792 0.74
SCHEMBL27666183 0.74 TSHR (0.56) PPARDLPAR3LPAR1LPAR2TSHR
SCHEMBL10426861 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209076-A1 USE OF IL-6 ANTIBODIES AND VEGF TRAPS, AND FUSION CONSTRUCTS AND CONJUGATES THEREOF KODIAK SCIENCES INC. 2024-06-27 US disclosed
US-20240197810-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC. 2024-06-20 US disclosed
WO-2024123791-A1 FORMULATIONS FOR DUAL VEGF/IL-6 INHIBITORS KODIAK SCIENCES INC. (US) 2024-06-13 WO disclosed
US-20230382983-A1 COMPLEMENT FACTOR D ANTAGONIST ANTIBODIES AND CONJUGATES THEREOF KODIAK SCIENCES INC. 2023-11-30 US disclosed
US-11819531-B2 Multifunctional zwitterionic polymer conjugates KODIAK SCIENCES INC. (US) 2023-11-21 US disclosed
EP-3659591-B1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2023-10-25 EP disclosed
US-20230277616-A9 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC. 2023-09-07 US disclosed
EP-4146168-A1 USE OF IL-6 ANTIBODIES AND VEGF TRAPS, AND FUSION CONSTRUCTS AND CONJUGATES THEREOF Kodiak Sciences Inc. (US) 2023-03-15 EP disclosed
US-11584790-B2 Complement factor D antagonist antibodies and conjugates thereof KODIAK SCIENCES INC. (US) 2023-02-21 US disclosed
EP-4029510-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS Kodiak Sciences Inc. (US) 2022-07-20 EP disclosed
EP-2558538-A2 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS Oligasis (US) 2013-02-20 EP disclosed
US-20130034517-A1 TARGETED DRUG PHOSPHORYLCHOLINE POLYMER CONJUGATES OLIGASIS (US) 2013-02-07 US disclosed
EP-2512462-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES Oligasis (US) 2012-10-24 EP disclosed
WO-2011130694-A2 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS OLIGASIS (US) 2011-10-20 WO disclosed
WO-2011075185-A1 TARGETED DRUG PHOSPHORYLCHOLINE POLYMER CONJUGATES OLIGASIS (US) 2011-06-23 WO disclosed
WO-2011075736-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2011-06-23 WO disclosed
US-20100166700-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates and Their Preparation OLIGASIS CORPORATION (US) 2010-07-01 US disclosed
EP-1988910-A2 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION Oligasis Corporation (US) 2008-11-12 EP disclosed
WO-2007100905-A2 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION NEXGEN THERAPEUTICS, LLC (US) 2007-09-07 WO disclosed
WO-2007100902-A2 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION OLIGASIS CORPORATION (US) 2007-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230277616-A9 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 BTN3A1 199/4885PPARD 4717/4885LPAR3 38/4885
US-20230382983-A1 COMPLEMENT FACTOR D ANTAGONIST ANTIBODIES AND CONJUGATES THEREOF CFD, CFH, CFB BTN3A1 1460/4885PPARD 1827/4885LPAR3 1033/4885
US-20130034517-A1 TARGETED DRUG PHOSPHORYLCHOLINE POLYMER CONJUGATES PHOSPHO1, EPHA2, PCTP BTN3A1 1715/4885PPARD 4442/4885LPAR3 9/4885
US-20100166700-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates and Their Preparation PHOSPHO1, PCTP, SGMS1 BTN3A1 1879/4885PPARD 4381/4885LPAR3 74/4885
US-20240209076-A1 USE OF IL-6 ANTIBODIES AND VEGF TRAPS, AND FUSION CONSTRUCTS AND CONJUGATES THEREOF IL6, FLT4, TEK BTN3A1 840/4885PPARD 4118/4885LPAR3 2953/4885
US-20240197810-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 BTN3A1 199/4885PPARD 4717/4885LPAR3 38/4885
US-11819531-B2 Multifunctional zwitterionic polymer conjugates PHOSPHO1, MSN, ZW10 BTN3A1 199/4885PPARD 4717/4885LPAR3 38/4885
US-11584790-B2 Complement factor D antagonist antibodies and conjugates thereof CFD, CFH, CFB BTN3A1 1460/4885PPARD 1827/4885LPAR3 1033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.