SCHEMBL514603

SCHEMBL514603

O=C1CC(C(=O)O)C(=O)N1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
MAP3K14 Q99558 1/20 0.44
CRBN Q96SW2 4/20 0.39
DDB1 Q16531 3/20 0.39
MEN1 O00255 1/20 0.37
APEX1 P27695 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ITGB3 P05106 2/20 0.35
ITGB1 P05556 2/20 0.35
ITGAV P06756 2/20 0.35
ITGB2 P05107 1/20 0.35
ITGA2B P08514 1/20 0.35
ITGA5 P08648 1/20 0.35
ITGB5 P18084 1/20 0.35
ITGAL P20701 1/20 0.35
CYP19A1 P11511 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GRM2 Q14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL15636563 0.96 ALDH1A1 (0.49) ALDH1A1MAP3K14CRBNDDB1MEN1
SCHEMBL21658858 0.83 MAP3K14 (0.46) ALDH1A1MAP3K14CRBNDDB1MEN1
SCHEMBL2711511 0.81 MAP3K14 (0.44) ALDH1A1MAP3K14CRBNDDB1MEN1
SCHEMBL2896147 0.79 MEN1 (0.47) ALDH1A1MAP3K14CRBNDDB1MEN1
SCHEMBL6511682 0.79 MAP3K14 (0.43) ALDH1A1MAP3K14CRBNDDB1MEN1
SCHEMBL27553051 0.79 MAP3K14 (0.43) ALDH1A1MAP3K14CRBNDDB1MEN1
SCHEMBL28506463 0.77 CRBN (0.56) CRBNDDB1
SCHEMBL10832091 0.77 CRBN (0.56) CRBNDDB1
SCHEMBL28505048 0.77 CRBN (0.56) CRBNDDB1
SCHEMBL8100037 0.76 MAP3K14 (0.40) ALDH1A1MAP3K14CRBNDDB1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116790136-B Carboxylic acid succinimide ester dye and reactive dyeing method thereof 现代纺织技术创新中心(鉴湖实验室) 2024-04-02 CN claimed
CN-116790136-A Carboxylic acid succinimide ester dye and reactive dyeing method thereof 现代纺织技术创新中心(鉴湖实验室) 2023-09-22 CN claimed
US-20230047529-A1 METHOD FOR SYNTHESIZING ZIRCONIUM COMPLEX JFE ENGINEERING CORPORATION (JP) 2023-02-16 US claimed
EP-4006015-A1 METHOD FOR SYNTHESIZING ZIRCONIUM COMPLEX JFE Engineering Corporation (JP) 2022-06-01 EP claimed
CN-101899327-B High-temperature equipment coke inhibitor and preparation and application thereof PETROCHINA CO LTD 2013-05-29 CN claimed
JP-8176105-A None JP disclosed
CN-118184988-A Preparation method of polyethylene glycol derivative and application of polyethylene glycol derivative in drug long-acting 江苏众红生物工程创药研究院有限公司 2024-06-14 CN disclosed
CN-118076606-A Imidazopyridazine IL-17 inhibitor compounds 詹森药业有限公司 2024-05-24 CN disclosed
CN-116790136-B Carboxylic acid succinimide ester dye and reactive dyeing method thereof 现代纺织技术创新中心(鉴湖实验室) 2024-04-02 CN disclosed
CN-116790136-B Carboxylic acid succinimide ester dye and reactive dyeing method thereof 现代纺织技术创新中心(鉴湖实验室) 2024-04-02 CN disclosed
CN-116790136-A Carboxylic acid succinimide ester dye and reactive dyeing method thereof 现代纺织技术创新中心(鉴湖实验室) 2023-09-22 CN disclosed
CN-116790136-A Carboxylic acid succinimide ester dye and reactive dyeing method thereof 现代纺织技术创新中心(鉴湖实验室) 2023-09-22 CN disclosed
US-4741818-A COMPLEXES LEARONAL, INC. (US) 1988-05-03 US disclosed
EP-0225422-A1 Alkaline baths and methods for electrodeposition of palladium and palladium alloys LeaRonal, Inc. (US) 1987-06-16 EP disclosed
US-4614712-A Immunoassays with luciferase labeled ligands or receptors THE UPJOHN COMPANY (US) 1986-09-30 US disclosed
US-4578378-A (Oxoheterocyclic carbonamido)cephem carboxylic acid derivatives SHIONOGI & CO., LTD. (JP) 1986-03-25 US disclosed
US-4548994-A IMMOBILIZATION ON AFFINITY RESIN THE UPJOHN COMPANY (US) 1985-10-22 US disclosed
EP-0057600-B1 AFFINITY RESINS AND THEIR USE IN ISOLATING BACTERIAL LUCIFERASE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1985-05-08 EP disclosed
US-4412001-A IMMOBILIZATION BY BINDING TO A LIGAND-SPACER-SUPPORT; WASHING; DESORPTION; PURIFICATION BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1983-10-25 US disclosed
EP-0057600-A2 Affinity resins and their use in isolating bacterial luciferase THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1982-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047529-A1 METHOD FOR SYNTHESIZING ZIRCONIUM COMPLEX ZRANB2, ZFP3, ZNF787 ALDH1A1 4708/4885MAP3K14 3001/4885CRBN 1720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.