Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21658858 | 0.81 | MAP3K14 (0.46) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL2711511 | 0.79 | MAP3K14 (0.44) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL514603 | 0.79 | ALDH1A1 (0.52) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL23855133 | 0.78 | CRBN (0.50) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL27553051 | 0.77 | MAP3K14 (0.43) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6511682 | 0.77 | MAP3K14 (0.43) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL4941968 | 0.77 | MAP3K14 (0.39) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| Cyclopropane SCHEMBL15636563 | 0.76 | ALDH1A1 (0.49) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL8100037 | 0.74 | MAP3K14 (0.40) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL19953555 | 0.74 | ALDH1A1 (0.73) | ALDH1A1TSHRSMN1; SMN2LMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179928-A1 | SUBSTITUTED SUCCINIMIDE-3-CARBOXAMIDES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-26 | — | — | WO | claimed |
| CN-110734796-B | Fuel soluble synergistic cleaning mixture for high pressure gasoline engines | 雅富顿化学公司 | 2023-04-14 | — | — | CN | disclosed |
| WO-2021252859-A1 | INHIBITORS OF APOL1 AND USE OF THE SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-12-16 | — | — | WO | disclosed |
| EP-3334721-B1 | CGRP RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2021-04-28 | — | — | EP | disclosed |
| CN-107922385-B | CGRP receptor antagonists | 伊莱利利公司 | 2020-09-08 | — | — | CN | disclosed |
| CN-111500329-A | Fuel additive mixture providing rapid injector cleaning in high pressure gasoline engines | 雅富顿化学公司 | 2020-08-07 | — | — | CN | disclosed |
| WO-2019179928-A1 | SUBSTITUTED SUCCINIMIDE-3-CARBOXAMIDES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179928-A1 | SUBSTITUTED SUCCINIMIDE-3-CARBOXAMIDES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-26 | — | — | WO | disclosed |
| US-9708297-B2 | CGRP receptor antagonists | ELI LILLY AND COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-20170044138-A1 | CGRP RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2017-02-16 | — | — | US | disclosed |
| US-20090031614-A1 | Environmentally-Friendly Fuel Compositions | AFTON CHEMICAL CORPORATION | 2009-02-05 | — | — | US | disclosed |
| US-20060168876-A1 | Fuels compositions and methods for using same | AFTON CHEMICAL CORPORATION | 2006-08-03 | — | — | US | disclosed |
| US-20050066572-A1 | Fuels compositions and methods for using same | AFTON CHEMICAL CORPORATION | 2005-03-31 | — | — | US | disclosed |
| EP-1518918-A1 | Fuels compositions and methods for using same | Afton Chemical Corporation (US) | 2005-03-30 | — | — | EP | disclosed |
| CN-1184195-C | Succinimide-acid compound and its derivative | ETHYL CORP (US) | 2005-01-12 | — | — | CN | disclosed |
| US-6548458-B2 | Prepared by reaction of hydrocarbyl-substituted succinic acylating agents with alpha-omega amino acids; pendant carboxylic acid moieties can be reacted with amines, alkoxylated amines and polyols; fuel additives | ETHYL CORPORATION | 2003-04-15 | — | — | US | disclosed |
| US-20020091068-A1 | Succinimide-acid compounds and derivatives thereof | AFTON CHEMICAL INTANGIBLES LLC | 2002-07-11 | — | — | US | disclosed |
| CN-1322712-A | Succinimide-acid compound and its derivative | ETHYL CORP (US) | 2001-11-21 | — | — | CN | disclosed |
| EP-1151994-A1 | Succinimide-acid compounds and derivatives thereof | ETHYL CORPORATION (US) | 2001-11-07 | — | — | EP | disclosed |
| US-4057432-A | PHOTOGRAPHIC COUPLERS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091068-A1 | Succinimide-acid compounds and derivatives thereof | SCD, DSG1, ELOVL1 | MEN1 3582/4885APEX1 2327/4885KMT2A 1351/4885 |
| US-20170044138-A1 | CGRP RECEPTOR ANTAGONISTS | CALCRL, CALCR, CCKBR | MEN1 1975/4885APEX1 4525/4885KMT2A 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.