Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21658858 | 0.81 | MAP3K14 (0.46) | MAP3K14CRBNALDH1A1LMNAMEN1 | |
| SCHEMBL1530916 | 0.81 | CRBN (0.41) | MAP3K14CRBNALDH1A1LMNAMEN1 | |
| SCHEMBL514603 | 0.79 | ALDH1A1 (0.52) | MAP3K14CRBNALDH1A1MEN1APEX1 | |
| SCHEMBL2711511 | 0.79 | MAP3K14 (0.44) | MAP3K14CRBNALDH1A1LMNAMEN1 | |
| SCHEMBL2896147 | 0.77 | MEN1 (0.47) | MAP3K14CRBNALDH1A1LMNAMEN1 | |
| SCHEMBL11022447 | 0.77 | TSHR (0.39) | MAP3K14CRBNALDH1A1KMT2ADDB1 | |
| SCHEMBL3263217 | 0.77 | MAP3K14 (0.43) | MAP3K14CRBNALDH1A1LMNAMEN1 | |
| Cyclopropane SCHEMBL15636563 | 0.76 | ALDH1A1 (0.49) | MAP3K14CRBNALDH1A1MEN1APEX1 | |
| SCHEMBL9644507 | 0.75 | MAP3K14 (0.34) | MAP3K14CRBNALDH1A1LMNAMEN1 | |
| SCHEMBL11361113 | 0.74 | CRBN (0.43) | MAP3K14CRBNALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3709807-A1 | PROCESS FOR REMOVAL OF BIOFILM | Whiteley Corporation Pty Ltd (AU) | 2020-09-23 | — | — | EP | claimed |
| CN-106668871-B | A kind of preparation method and application for the Photosensitive magnetic nano particle system inhibiting breast cancer cell growth | 华南师范大学 | 2019-08-06 | — | — | CN | claimed |
| EP-0799291-B1 | ENGINE OIL WITH IMPROVED FUEL ECONOMY PROPERTIES | EXXONMOBIL RES & ENG CO (US) | 2002-03-20 | — | — | EP | claimed |
| CN-106668871-B | A kind of preparation method and application for the Photosensitive magnetic nano particle system inhibiting breast cancer cell growth | 华南师范大学 | 2019-08-06 | — | — | CN | disclosed |
| CN-107219292-A | A kind of method of mass-spectrometric technique detection protein conformation change | 中国科学院大连化学物理研究所 | 2017-09-29 | — | — | CN | disclosed |
| US-8697065-B2 | Non-natural ribonuclease conjugates as cytotoxic agents | QUINTESSENCE BIOSCIENCES, INC. (US) | 2014-04-15 | — | — | US | disclosed |
| WO-2013148178-A1 | QUANTIFICATION OF POST-TRANSLATIONAL MODIFICATIONS ON HISTONE PROTEINS WITH MASS SPECTROMETRY | THE BROAD INSTITUTE, INC. (US) | 2013-10-03 | — | — | WO | disclosed |
| US-8470315-B2 | Non-natural ribonuclease conjugates as cytotoxic agents | QUINTESSENCE BIOSCIENCES, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20050261232-A1 | Non-natural ribonuclease conjugates as cytotoxic agents | QUINTESSENCE BIOSCIENCES, INC. (US) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261232-A1 | Non-natural ribonuclease conjugates as cytotoxic agents | RNASE1, RNASEL, RNASEH1 | MAP3K14 4036/4885CRBN 2067/4885ALDH1A1 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.