Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046978 | 0.87 | HTR1A (0.63) | CYP1A2KDM4EGAATUBB1CA1 | |
| SCHEMBL9046973 | 0.87 | HTR1A (0.63) | CYP1A2KDM4EGAATUBB1CA1 | |
| SCHEMBL9044602 | 0.82 | KDM4E (0.64) | PTGS1PTGS2CYP1A2KDM4ENFE2L2 | |
| SCHEMBL9044613 | 0.82 | KDM4E (0.64) | PTGS1PTGS2CYP1A2KDM4ENFE2L2 | |
| SCHEMBL17361873 | 0.79 | CYP1A1 (0.55) | PTGS1PTGS2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL17361874 | 0.79 | CYP1A1 (0.55) | PTGS1PTGS2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL2492516 | 0.79 | PTGS1 (0.54) | PTGS1PKMPTGS2CYP3A4CYP2B6 | |
| SCHEMBL807443 | 0.79 | ABL1 (0.59) | PTGS1PKMPTGS2CYP3A4CYP2B6 | |
| SCHEMBL1457517 | 0.79 | ABL1 (0.59) | PTGS1PKMPTGS2CYP3A4CYP2B6 | |
| SCHEMBL29603846 | 0.79 | ABL1 (0.59) | PTGS1PKMPTGS2CYP3A4CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190247317-A1 | ICAM-1 TARGETING ELPS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2019-08-15 | — | — | US | disclosed |
| US-20150238431-A1 | ICAM-1 TARGETING ELPS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-08-27 | — | — | US | disclosed |
| WO-2014059384-A2 | ICAM-1 TARGETING ELPs | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-04-17 | — | — | WO | disclosed |
| US-20130236416-A1 | SURFACE MODIFIED COLLOIDAL PARTICLES | CLEMSON UNIVERSITY (US) | 2013-09-12 | — | — | US | disclosed |
| US-20070069122-A1 | In situ polypeptide identification | HOFFMANN-LA ROCHE INC. | 2007-03-29 | — | — | US | disclosed |
| US-7176280-B2 | Isolated polypeptides and compositions from the venom of P. transvaalicus and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-13 | — | — | US | disclosed |
| EP-1729133-A1 | Transthyretin as marker for nephrotoxicity | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-06 | — | — | EP | disclosed |
| EP-1729134-A1 | In situ biomarker identification | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-06 | — | — | EP | disclosed |
| US-20030113892-A1 | Isolated polypeptides and compositions from the venom of P. transvaalicus and methods of use | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2003-06-19 | — | — | US | disclosed |
| WO-2003028666-A2 | ISOLATED POLYPEPTIDES AND COMPOSITIONS FROM THE VENOM OF P. TRANSVAALICUS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-04-10 | — | — | WO | disclosed |