Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.48 |
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901848 | 0.82 | CYP3A4 (0.61) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL1791116 | 0.81 | PTGS1 (0.54) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL5146748 | 0.79 | PTGS1 (0.63) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL1788486 | 0.78 | PTGS1 (0.48) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL2852406 | 0.75 | ALOX5 (0.70) | PKMCYP1A2CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL13237036 | 0.72 | ALOX5 (0.79) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL14875131 | 0.72 | ALOX5 (0.79) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL807443 | 0.72 | ABL1 (0.59) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL29603846 | 0.72 | ABL1 (0.59) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL1457517 | 0.72 | ABL1 (0.59) | PTGS1PKMPTGS2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580775-B2 | Use of derivatives of sinapinic acid and compositions comprising such derivatives | COGNIS IP MANAGEMENT GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| EP-2117499-B1 | Use of sinapic acid in non-therapeutic cosmetic and/or topical compositions | COGNIS IP MAN GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20100130605-A1 | Use of Derivatives of Sinapinic Acid and Compositions Comprising Such Derivatives | COGNIS IP MANAGEMENT GMBH (DE) | 2010-05-27 | — | — | US | disclosed |
| EP-2117499-A1 | USE OF DERIVATIVES OF SINAPINIC ACID AND COMPOSITIONS COMPRISING SUCH DERIVATIVES | Cognis IP Management GmbH (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008107093-A1 | USE OF DERIVATIVES OF SINAPINIC ACID AND COMPOSITIONS COMPRISING SUCH DERIVATIVES | COGNIS IP MANAGEMENT GMBH (DE) | 2008-09-12 | — | — | WO | disclosed |
| EP-1967175-A1 | Use of derivatives of sinapinic acid and compositions comprising such derivatives | Cognis IP Management GmbH (DE) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130605-A1 | Use of Derivatives of Sinapinic Acid and Compositions Comprising Such Derivatives | TYR, ASAH1, AANAT | PTGS1 449/4885PKM 1859/4885PTGS2 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.