Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betaine SCHEMBL3946024 | 0.95 | TSHR (0.35) | TSHRALDH1A1LMNAAPEX1 | |
| SCHEMBL7722290 | 0.89 | BBOX1 (0.32) | — | |
| Water SCHEMBL170463 | 0.88 | BBOX1 (0.31) | — | |
| Betaine SCHEMBL5613071 | 0.82 | TSHR (0.35) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL3265675 | 0.80 | TSHR (0.33) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL11147482 | 0.79 | TSHR (0.39) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL6917420 | 0.78 | TSHR (0.38) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL7991073 | 0.78 | TSHR (0.35) | TSHRALDH1A1LMNAAPEX1 | |
| SCHEMBL173751 | 0.77 | BBOX1 (0.49) | LMNA | |
| Glycinebetaine SCHEMBL5166113 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544812-B1 | IMPROVED MICROCAPSULES AND PRODUCTION THEREOF | FOLLMANN GMBH & CO KG (DE) | 2018-10-24 | — | — | EP | claimed |
| EP-1902077-B2 | NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD | OREAL (FR) | 2018-07-18 | — | — | EP | claimed |
| US-10004923-B2 | Neutralised cationic polymer, composition containing said polymer and a cosmetic treatment method | L'OREAL (FR) | 2018-06-26 | — | — | US | claimed |
| US-20160177002-A1 | HYDROGEL FIBERS AND PREPARATION THEREOF | INTELLISIV LTD. (IL) | 2016-06-23 | — | — | US | claimed |
| EP-3027233-A1 | HYDROGEL FIBERS AND PREPARATION THEREOF | Intellisiv Ltd (IL) | 2016-06-08 | — | — | EP | claimed |
| US-9359461-B2 | Ethylene copolymers, compositions comprising same and preparation and treatment methods | L'OREAL (FR) | 2016-06-07 | — | — | US | claimed |
| EP-2705062-B1 | SHEAR STABLE POLYMERS, THEIR PREPARATION AND THEIR USE AS THICKENER | RHODIA OPERATIONS (FR) | 2016-03-23 | — | — | EP | claimed |
| US-9196405-B2 | Stable iron oxide nanoparticles and method of production | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2015-11-24 | — | — | US | claimed |
| US-9056125-B2 | Films for controlled cell growth and adhesion | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2015-06-16 | — | — | US | claimed |
| WO-2015015500-A1 | HYDROGEL FIBERS AND PREPARATION THEREOF | INTELLISIV LTD. (IL) | 2015-02-05 | — | — | WO | claimed |
| EP-1768643-A2 | COSMETIC COMPOSITIONS CONTAINING AT LEAST ONE SURFACTANT AND AT LEAST ONE ETHYLENE COPOLYMER WITH POLYETHYLENE GLYCOL GRAFTS | L'OREAL (FR) | 2007-04-04 | — | — | EP | claimed |
| EP-1769011-A2 | NOVEL ETHYLENE COPOLYMERS, COMPOSITIONS CONTAINING SAID COPOLYMERS AND TREATMENT METHOD | L'Oréal (FR) | 2007-04-04 | — | — | EP | claimed |
| EP-1765893-A2 | NOVEL ETHYLENE COPOLYMERS, COMPOSITIONS COMPRISING SAME AND PREPARATION AND TREATMENT METHODS | L'Oréal (FR) | 2007-03-28 | — | — | EP | claimed |
| WO-2007003784-A1 | NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD | L'OREAL (FR) | 2007-01-11 | — | — | WO | claimed |
| EP-1732964-A2 | SEQUENCED COPOLYMER | Arkema France (FR) | 2006-12-20 | — | — | EP | claimed |
| WO-2006013269-A2 | NOVEL ETHYLENE COPOLYMERS, COMPOSITIONS COMPRISING SAME AND PREPARATION AND TREATMENT METHODS | L'OREAL (FR) | 2006-02-09 | — | — | WO | claimed |
| WO-2006013270-A2 | COSMETIC COMPOSITIONS CONTAINING AT LEAST ONE SURFACTANT AND AT LEAST ONE ETHYLENE COPOLYMER WITH POLYETHYLENE GLYCOL GRAFTS | L'ORÉAL (FR) | 2006-02-09 | — | — | WO | claimed |
| WO-2006013268-A2 | NOVEL ETHYLENE COPOLYMERS, COMPOSITIONS CONTAINING SAID COPOLYMERS AND TREATMENT METHOD | L'OREAL (FR) | 2006-02-09 | — | — | WO | claimed |
| US-20050287111-A1 | Films for controlled cell growth and adhesion | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-12-29 | — | — | US | claimed |
| WO-2005103102-A2 | SEQUENCED COPOLYMER | ARKEMA FRANCE (FR) | 2005-11-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004923-B2 | Neutralised cationic polymer, composition containing said polymer and a cosmetic treatment method | KRT18, EYA3, EYA2 | TSHR 1215/4885ALDH1A1 3858/4885LMNA 2637/4885 |
| US-20050287111-A1 | Films for controlled cell growth and adhesion | PCNA, FIBP, FSCN1 | TSHR 1078/4885ALDH1A1 4613/4885LMNA 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.