Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035596 | 0.75 | SLC6A2 (0.47) | KDM4ESLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL2611076 | 0.70 | ALDH1A1 (0.47) | KDM4ELMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL1654659 | 0.68 | CYP3A4 (0.54) | KDM4ELMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL12045706 | 0.68 | ALDH1A1 (0.42) | KDM4ELMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL19283998 | 0.67 | ALDH1A1 (0.44) | KDM4ELMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL19283903 | 0.67 | LMNA (0.47) | KDM4ELMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL325226 | 0.66 | LMNA (0.46) | KDM4ELMNAMEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL7450279 | 0.66 | KDM4E (0.42) | KDM4ELMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL14237602 | 0.66 | FABP1 (0.57) | KDM4ELMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL514723 | 0.66 | SUCNR1 (0.43) | KDM4ELMNAMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028997-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | COATS STEVEN J (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028997-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | PROKR1, PROKR2, GIPR | KDM4E 4866/4885LMNA 794/4885MEN1 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.