Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721397 | 0.90 | L3MBTL1 (0.65) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL11810082 | 0.89 | L3MBTL1 (0.64) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL8853547 | 0.89 | L3MBTL1 (0.64) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL7754703 | 0.89 | L3MBTL1 (0.64) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL11658254 | 0.89 | L3MBTL1 (0.64) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL10783529 | 0.87 | L3MBTL1 (0.84) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL10595519 | 0.85 | L3MBTL1 (0.74) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL17445913 | 0.85 | L3MBTL1 (0.74) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL73790 | 0.85 | PPARD (0.54) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL12969843 | 0.84 | L3MBTL1 (0.67) | L3MBTL1MAPTNPSR1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028363-A | Method of casting powder materials | NKK CORPORATION (JP) | 1991-07-02 | — | — | US | claimed |
| US-10457669-B2 | Benzolactam compounds as protein kinase inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-10-29 | — | — | US | disclosed |
| US-20190047990-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-02-14 | — | — | US | disclosed |
| EP-1353542-B1 | Process for production of multilayered wiring board | NGK SPARK PLUG CO (JP) | 2018-05-16 | — | — | EP | disclosed |
| US-20170166584-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-20080004287-A1 | Substituted Piperidines that Increase P53 Activity and the Uses Thereof | SCHERING CORPORATION | 2008-01-03 | — | — | US | disclosed |
| US-7309669-B2 | Glass powder SiO2, B2O3, 1a element and optionally 2a element and Al2O3; ceramic filler containing Al2O3, SiO2 or 3Al2O3*2SiO2 and 1a element and optionally 2a element; low temperature-sintering material; crystals having superior high-frequency characteristics crystallize during sintering | NGK SPARK PLUG CO., LTD. (JP) | 2007-12-18 | — | — | US | disclosed |
| US-20060083930-A1 | Glass powder SiO2, B2O3, 1a element and optionally 2a element and Al2O3; ceramic filler containing Al2O3, SiO2 or 3Al2O3*2SiO2 and 1a element and optionally 2a element; low temperature-sintering material; crystals having superior high-frequency characteristics crystallize during sintering | NGK SPARK PLUG CO., LTD. | 2006-04-20 | — | — | US | disclosed |
| EP-0875781-B1 | Liquid crystal alignment layer, production method for the same, and liquid crystal display device comprising the same | JSR CORP (JP) | 2005-08-17 | — | — | EP | disclosed |
| EP-0840161-B1 | LIQUID CRYSTAL ALIGNING AGENT | JSR CORP (JP) | 2005-04-06 | — | — | EP | disclosed |
| WO-1990003955-A1 | METAL OXIDE DIELECTRIC DENSE BODIES, PRECURSOR POWDERS THEREFOR, AND METHODS FOR PREPARING SAME | RAYCHEM CORPORATION (US) | 1990-04-19 | — | — | WO | disclosed |
| EP-0210874-B1 | THIN TAPE FOR DIELECTRIC MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| WO-1988008413-A1 | STRENGTHENED CORDIERITE HAVING MINOR AMOUNTS OF CALCIA | THE DOW CHEMICAL COMPANY (US) | 1988-11-03 | — | — | WO | disclosed |
| US-4752857-A | DIELECTRIC CERAMICS, CELLULOSE | THE DOW CHEMICAL COMPANY (US) | 1988-06-21 | — | — | US | disclosed |
| US-4745092-A | Strengthened cordierite having minor amounts of calcia | THE DOW CHEMICAL COMPANY (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0210874-A1 | Thin tape for dielectric materials | THE DOW CHEMICAL COMPANY (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4641221-A | ETHYL CELLULOSE BINDER; GREEN STRENGHT; MULTILAYER CAPACITORS | THE DOW CHEMICAL COMPANY (US) | 1987-02-03 | — | — | US | disclosed |
| US-4388081-A | CONTAINING PHENOXYALCOHOL AS ANTINKNOCK ADDITIVE | PHILLIPS PETROLEUM COMPANY (US) | 1983-06-14 | — | — | US | disclosed |
| US-4255152-A | USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-3945961-A | Novel cross-linking agents and their use in electrophoretic coating composition | AMERICAN CYANAMID COMPANY (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004287-A1 | Substituted Piperidines that Increase P53 Activity and the Uses Thereof | TP53, MDM2, TP53BP1 | L3MBTL1 2415/4885MAPT 2712/4885NPSR1 3937/4885 |
| US-20190047990-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | L3MBTL1 914/4885MAPT 458/4885NPSR1 3589/4885 |
| US-10457669-B2 | Benzolactam compounds as protein kinase inhibitors | MAPK1, ALK, MAP3K1 | L3MBTL1 914/4885MAPT 458/4885NPSR1 3589/4885 |
| US-20170166584-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT1 | L3MBTL1 2994/4885MAPT 2092/4885NPSR1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.