Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 5/20 | 0.34 |
| ▸ | SKP1 | P63208 | 5/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514737 | 1.00 | SLC6A7 (0.40) | SLC6A7CKS1BSKP1SKP2KMT2A | |
| SCHEMBL512699 | 0.83 | AKT1 (0.45) | SLC6A7KMT2AAKT1AKT2 | |
| SCHEMBL512700 | 0.83 | AKT1 (0.45) | SLC6A7KMT2AAKT1AKT2 | |
| SCHEMBL10141150 | 0.83 | AKT1 (0.45) | SLC6A7KMT2AAKT1AKT2 | |
| SCHEMBL14876924 | 0.83 | SLC6A7 (0.42) | SLC6A7CKS1BSKP1SKP2KMT2A | |
| SCHEMBL14876926 | 0.83 | SLC6A7 (0.42) | SLC6A7CKS1BSKP1SKP2KMT2A | |
| SCHEMBL514025 | 0.78 | XIAP (0.37) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL514026 | 0.78 | XIAP (0.37) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL513116 | 0.78 | ALDH1A1 (0.47) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL513117 | 0.78 | ALDH1A1 (0.47) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028918-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF MAKING SAME | GLAXO WELLCOME MANUFACTURING PTE LTD. (SG) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028918-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF MAKING SAME | PIK3CA, G6PC1, PIK3C2B | SLC6A7 3292/4885CKS1B 568/4885SKP1 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.