SCHEMBL5147481

SCHEMBL5147481

Cc1cc(N(C)C)ccc1C1(c2c(C)[nH]c3ccccc23)OC(=O)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.47
LMNA P02545 6/20 0.47
NPSR1 Q6W5P4 3/20 0.47
POLB P06746 2/20 0.47
ALOX12 P18054 2/20 0.47
GPR55 Q9Y2T6 1/20 0.47
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
HPGD P15428 2/20 0.46
HIF1A Q16665 2/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
HTT P42858 2/20 0.40
FTO Q9C0B1 2/20 0.40
CYP2C19 P33261 2/20 0.40
USP2 O75604 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11244641 0.91 ALDH1A1 (0.45) MAPTLMNANPSR1POLBALOX12
SCHEMBL4578036 0.89 MAPT (0.45) MAPTLMNANPSR1POLBALOX12
SCHEMBL9245862 0.86 LMNA (0.43) MAPTLMNANPSR1POLBALOX12
SCHEMBL29383061 0.86 ALDH1A1 (0.51) MAPTLMNANPSR1POLBALOX12
SCHEMBL337223 0.86 ALDH1A1 (0.51) MAPTLMNANPSR1POLBALOX12
SCHEMBL13382768 0.85 MAPT (0.41) MAPTLMNANPSR1POLBALOX12
SCHEMBL10350354 0.84 ALDH1A1 (0.65) MAPTLMNANPSR1POLBALOX12
SCHEMBL31715256 0.84 LMNA (0.42) MAPTLMNANPSR1POLBALOX12
SCHEMBL10528872 0.84 LMNA (0.42) MAPTLMNANPSR1POLBALOX12
SCHEMBL3228674 0.83 LMNA (0.50) MAPTLMNANPSR1POLBALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7270928-B2 Isocyanate composition, microcapsule and production method thereof, and recording material FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed
EP-1382385-B1 Microcapsule and process for manufacturing the same FUJIFILM CORP (JP) 2007-03-21 EP disclosed
US-7011922-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-03-14 US disclosed
US-20050272604-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-12-08 US disclosed
EP-1598208-A2 Heat-sensitive recording material Fuji Photo Film Co., Ltd. (JP) 2005-11-23 EP disclosed
US-6919297-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2005-07-19 US disclosed
US-20050153839-A1 Isocyanate composition, microcapsule and production method thereof, and recording material FUJI PHOTO FILM CO., LTD. 2005-07-14 US disclosed
US-6881810-B2 Microcapsule and process for manufacturing the same FUJI PHOTO FILM CO., LTD. (JP) 2005-04-19 US disclosed
EP-0992364-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 2005-01-12 EP disclosed
EP-0992363-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 2004-09-22 EP disclosed
US-20020091065-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2002-07-11 US disclosed
US-6303259-B1 FOR COLOR DUPLICATORS, COLOR PRINTERS, ETC MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2001-10-16 US disclosed
EP-0992363-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-04-12 EP disclosed
EP-0992364-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-04-12 EP disclosed
EP-0754564-B1 Heat sensitive recording material and recording method. MITSUBISHI PAPER MILLS LTD (JP) 2000-03-01 EP disclosed
US-5916680-A CONTAINING A DIAZO COMPOUND OR AN ELECTRON DONATIVE DYE PRECURSOR, WHEREIN THE CAPSULE WALL IS COMPOSED OF AT LEAST ONE POLYMER OBTAINED BY POLYMERIZATION OF AN ISOCYANATE COMPOUND CONTAINING AN ADDUCT FUJI PHOTO FILM CO., LTD (JP) 1999-06-29 US disclosed
US-5876898-A MULTICOLOR RECORDING OF HIGH CONTRAST MITSUBISHI PAPER MILLS LIMITED (JP) 1999-03-02 US disclosed
EP-0754564-A2 Heat sensitive recording material and recording method using the same MITSUBISHI PAPER MILLS, LTD. (JP) 1997-01-22 EP disclosed
US-5486446-A Multi-color heat-sensitive recording material utilizing multiple diazonium salt layers FUJI PHOTO FILM CO., LTD. (JP) 1996-01-23 US disclosed
US-5409880-A Having intermediate layers containing gelatin or phthalized gelatin and homopolymer or copolymer of vinylpyrrolidone in specified amounts FUJI PHOTO FILM CO., LTD. (JP) 1995-04-25 US disclosed