Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL142027 | 0.85 | MGLL (0.34) | — | |
| Hydrochloric Acid SCHEMBL23142695 | 0.85 | MGLL (0.34) | — | |
| SCHEMBL141305 | 0.84 | MGLL (0.35) | — | |
| SCHEMBL9314254 | 0.81 | MGLL (0.34) | — | |
| Hydrochloric Acid SCHEMBL4074680 | 0.80 | MGLL (0.46) | ALDH1A1CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL11061516 | 0.79 | EPHX2 (0.32) | ALDH1A1CNR1CNR2 | |
| Water SCHEMBL6549696 | 0.78 | MGLL (0.46) | ALDH1A1CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL11253281 | 0.78 | EEF2K (0.37) | ALDH1A1 | |
| SCHEMBL16887389 | 0.76 | MGLL (0.35) | — | |
| Sulfuric Acid SCHEMBL4376501 | 0.74 | EPHX2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1767192-A2 | Cationic lipid compositions targeting angiogenic endothelial cells | The Regents of the University of California (US) | 2007-03-28 | — | — | EP | disclosed |