Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974790 | 0.89 | — | — | |
| SCHEMBL5147508 | 0.86 | PLA2G7 (0.34) | PLA2G7ALDH1A1GRM2 | |
| SCHEMBL5145980 | 0.85 | MAPK8 (0.34) | PLA2G7ALDH1A1GRM2 | |
| SCHEMBL5148389 | 0.84 | CA1 (0.35) | PLA2G7ALDH1A1GRM2 | |
| SCHEMBL5147316 | 0.79 | PLA2G7 (0.39) | PLA2G7ALDH1A1GRM2 | |
| SCHEMBL5148399 | 0.79 | PLA2G7 (0.39) | PLA2G7ALDH1A1GRM2 | |
| SCHEMBL2980215 | 0.77 | — | — | |
| SCHEMBL2980503 | 0.76 | — | — | |
| SCHEMBL2971299 | 0.74 | — | — | |
| SCHEMBL5147336 | 0.74 | PLA2G7 (0.35) | PLA2G7ALDH1A1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831207-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006066172-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | AMGEN, INC. (US) | 2006-06-22 | — | — | WO | disclosed |