Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL7266577 | 0.95 | ALOX5 (0.33) | FDPSALOX5PDK2 | |
| SCHEMBL1755298 | 0.92 | FDPS (0.38) | FDPSALOX5PDK2TP53GAA | |
| Ethylene SCHEMBL7266572 | 0.91 | ALOX5 (0.31) | FDPSALOX5 | |
| SCHEMBL4581912 | 0.90 | ALOX5 (0.30) | ALOX5 | |
| SCHEMBL680174 | 0.86 | FDPS (0.35) | FDPSALOX5PDK2TP53GAA | |
| SCHEMBL7777147 | 0.85 | PDK2 (0.41) | FDPSALOX5PDK2TP53GAA | |
| SCHEMBL14156864 | 0.81 | ALOX5 (0.32) | FDPSALOX5PDK2TP53TDP1 | |
| SCHEMBL12522717 | 0.81 | ALOX5 (0.32) | FDPSALOX5PDK2TP53GSTO1 | |
| SCHEMBL680181 | 0.81 | ALOX5 (0.32) | FDPSALOX5PDK2TP53GSTO1 | |
| SCHEMBL12379453 | 0.81 | FDPS (0.34) | FDPSALOX5PDK2GGPS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288617-B2 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2007-10-30 | — | — | US | disclosed |
| US-20040135131-A1 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2004-07-15 | — | — | US | disclosed |