SCHEMBL680174

SCHEMBL680174

Cc1ccc(C)c(C2(c3ccc(OCCC(C)CCCC(C)C)cc3)c3cc(Br)ccc3-c3ccc(Br)cc32)c1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.35
ALOX5 P09917 1/20 0.35
PDK2 Q15119 1/20 0.33
TP53 P04637 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
GAA P10253 1/20 0.31
ALOX12 P18054 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GGPS1 O95749 1/20 0.31
GSTO1 P78417 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14156864 0.95 ALOX5 (0.32) FDPSALOX5PDK2TP53TDP1
SCHEMBL1755298 0.94 FDPS (0.38) FDPSALOX5PDK2TP53TDP1
SCHEMBL5999278 0.89 PDK2 (0.38) FDPSALOX5PDK2DRD2DRD4
SCHEMBL28748237 0.87 TDP1 (0.35) FDPSALOX5PDK2TP53DRD2
SCHEMBL7777147 0.87 PDK2 (0.41) FDPSALOX5PDK2TP53TDP1
SCHEMBL5147627 0.86 FDPS (0.35) FDPSALOX5PDK2TP53TDP1
SCHEMBL12522717 0.83 ALOX5 (0.32) FDPSALOX5PDK2TP53TDP1
SCHEMBL680181 0.83 ALOX5 (0.32) FDPSALOX5PDK2TP53TDP1
Di(Hydroxyethyl)Ether SCHEMBL7266577 0.82 ALOX5 (0.33) FDPSALOX5PDK2
SCHEMBL12379453 0.81 FDPS (0.34) FDPSALOX5PDK2TDP1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8878163-B2 Light-emitting device and 9.9 biphenyl fluorene materials therefor CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-11-04 US disclosed
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 US disclosed
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-7910687-B2 Conjugated polymers containing arylamine units, the representation thereof and the use of the same MERCK PATENT GMBH (DE) 2011-03-22 US disclosed
US-7910687-B2 Conjugated polymers containing arylamine units, the representation thereof and the use of the same MERCK PATENT GMBH (DE) 2011-03-22 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
US-20100276674-A1 Light-emitting Device and Materials Therefor CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2010-11-04 US disclosed
EP-1381639-B1 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF COVION ORGANIC SEMICONDUCTORS (DE) 2004-09-08 EP disclosed
US-20040135131-A1 Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof MERCK PATENT GMBH (DE) 2004-07-15 US disclosed
EP-1123336-B1 CONJUGATED POLYMERS CONTAINING SPECIAL FLUORENE STRUCTURAL ELEMENTS WITH IMPROVED PROPERTIES COVION ORGANIC SEMICONDUCTORS (DE) 2004-03-10 EP disclosed
EP-1381639-A1 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF Covion Organic Semiconductors GmbH (DE) 2004-01-21 EP disclosed
EP-1370619-A1 SOLUTIONS AND DISPERSIONS OF ORGANIC SEMICONDUCTORS Covion Organic Semiconductors GmbH (DE) 2003-12-17 EP disclosed
US-6653438-B1 Semiconductors and/or electroluminescent material COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2003-11-25 US disclosed
WO-2002077060-A1 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-10-03 WO disclosed
WO-2002072714-A1 SOLUTIONS AND DISPERSIONS OF ORGANIC SEMICONDUCTORS COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-09-19 WO disclosed
EP-1123336-A1 CONJUGATED POLYMERS CONTAINING SPECIAL FLUORENE STRUCTURAL ELEMENTS WITH IMPROVED PROPERTIES Celanese Ventures GmbH (DE) 2001-08-16 EP disclosed
WO-2000022026-A1 CONJUGATED POLYMERS CONTAINING SPECIAL FLUORENE STRUCTURAL ELEMENTS WITH IMPROVED PROPERTIES CELANESE VENTURES GMBH (DE) 2000-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100276674-A1 Light-emitting Device and Materials Therefor SLC39A11, LEF1, FARSB FDPS 154/4885ALOX5 2936/4885PDK2 3009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.