SCHEMBL5147899

SCHEMBL5147899

NC(=O)c1ccnc(CCO)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.51
KDM4E B2RXH2 1/20 0.51
LMNA P02545 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP1A2 P05177 2/20 0.45
POLB P06746 1/20 0.45
KDM5C P41229 4/20 0.44
KDM5B Q9UGL1 3/20 0.44
KDM4C Q9H3R0 2/20 0.44
KDM5A P29375 1/20 0.44
KDM5D Q9BY66 1/20 0.44
KDM4B O94953 2/20 0.43
MBOAT4 Q96T53 1/20 0.42
MKNK1 Q9BUB5 2/20 0.40
MKNK2 Q9HBH9 2/20 0.40
PARP10 Q53GL7 1/20 0.40
PRKCI P41743 1/20 0.38
CSNK2A1 P68400 1/20 0.38
HIPK2 Q9H2X6 1/20 0.38
GABRP O00591 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16115747 0.90 KDM4E (0.49) TSHRKDM4ELMNACYP3A4CYP1A2
SCHEMBL8594535 0.85 CYP1A2 (0.47) TSHRKDM4ELMNACYP3A4CYP1A2
SCHEMBL30607268 0.85 CYP1A2 (0.47) TSHRKDM4ELMNACYP3A4CYP1A2
SCHEMBL17873933 0.84 KDM4E (0.73) TSHRKDM4ELMNACYP3A4CYP1A2
SCHEMBL6637823 0.82 TSHR (0.47) TSHRKDM4ELMNACYP3A4CYP1A2
SCHEMBL7668183 0.81 CYP1A2 (0.47) TSHRKDM4ELMNACYP3A4CYP1A2
SCHEMBL509023 0.81 CYP1A2 (0.47) TSHRKDM4ELMNACYP3A4CYP1A2
SCHEMBL3634347 0.81 KDM4E (0.59) TSHRKDM4ELMNACYP3A4CYP1A2
SCHEMBL1568234 0.80 NR3C2 (0.51) TSHRKDM4ELMNACYP3A4POLB
SCHEMBL3630367 0.80 KDM4E (0.58) TSHRKDM4ELMNACYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118059303-A Shape memory material with chelating system and preparation method thereof 深圳先进技术研究院 2024-05-24 CN claimed
CN-117603426-A Post-crosslinking amphiphilic polyurethane, preparation method thereof and application thereof in glucose sensor 江苏鱼跃凯立特生物科技有限公司 2024-02-27 CN claimed
CN-116478978-A Digestion method of coal mine gas, composite carrier, gas digestion solution and preparation of composite carrier and gas digestion solution 重庆大学 2023-07-25 CN claimed
CN-110512308-B Linear bicomponent filaments, fibres or tapes 纳米及先进材料研发院有限公司 2022-03-22 CN claimed
CN-109206620-B Bionic water response shape memory polyamino acid material and preparation method thereof 香港理工大学深圳研究院 2021-08-20 CN claimed
CN-108559048-B PH value sensitive biodegradable polyurethane urea material and preparation method thereof 山东师范大学 2021-01-08 CN claimed
CN-103030957-B A kind of material based on poly-hydroxy fatty acid and its preparation method and application SHENZHEN UNIVERSITY (CN) 2015-08-05 CN claimed
US-7105214-B2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 2006-09-12 US claimed
US-20030124320-A1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION 2003-07-03 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
US-5657064-A Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1997-08-12 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
CN-118059303-A Shape memory material with chelating system and preparation method thereof 深圳先进技术研究院 2024-05-24 CN disclosed
CN-117603426-A Post-crosslinking amphiphilic polyurethane, preparation method thereof and application thereof in glucose sensor 江苏鱼跃凯立特生物科技有限公司 2024-02-27 CN disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP disclosed