Fluoride Ion

Fluoride Ion

SCHEMBL5148077

C=CC[n+]1cccc(C(=O)O)c1.[F-]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP2D6 P10635 1/20 0.39
PABPC1 P11940 1/20 0.39
ATM Q13315 1/20 0.39
HSP90AA1 P07900 4/20 0.38
DAO P14920 1/20 0.38
TSHR P16473 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
GLA P06280 1/20 0.38
AKT1 P31749 1/20 0.36
MAPT P10636 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14387378 0.98 KMT2A (0.49) KMT2AMEN1L3MBTL1NPSR1CYP2D6
Hydrochloric Acid SCHEMBL2810290 0.97 KMT2A (0.47) KMT2AMEN1L3MBTL1NPSR1CYP2D6
Bromide SCHEMBL5148139 0.97 KMT2A (0.47) KMT2AMEN1L3MBTL1NPSR1CYP2D6
Fluoride Ion SCHEMBL5149210 0.85 NPSR1 (0.55) KMT2AMEN1L3MBTL1NPSR1ATM
Bromide SCHEMBL9432590 0.84 ALDH1A1 (0.45) KMT2AMEN1L3MBTL1NPSR1CYP2D6
SCHEMBL11383237 0.83 USP2 (0.50) KMT2AMEN1L3MBTL1NPSR1CYP2D6
Hydrochloric Acid SCHEMBL2810174 0.82 NPSR1 (0.55) KMT2AMEN1L3MBTL1NPSR1ATM
Bromide SCHEMBL5149080 0.82 NPSR1 (0.55) KMT2AMEN1L3MBTL1NPSR1ATM
SCHEMBL9811331 0.79 KMT2A (0.53) KMT2AMEN1L3MBTL1NPSR1CYP2D6
Bromide SCHEMBL8588064 0.78 HSP90AA1 (0.45) KMT2AMEN1L3MBTL1NPSR1PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1870495-A1 Aqueous alkaline, cyanide-free, bath for the galvanic deposition of Zinc and Zinc alloy layers ATOTECH DEUTSCHLAND GMBH (DE) 2007-12-26 EP disclosed