Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.49 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL5149210 | 0.97 | NPSR1 (0.55) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2810174 | 0.97 | NPSR1 (0.55) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| Bromide SCHEMBL5148139 | 0.85 | KMT2A (0.47) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL14387378 | 0.83 | KMT2A (0.49) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| Bromide SCHEMBL9432590 | 0.83 | ALDH1A1 (0.45) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2810290 | 0.82 | KMT2A (0.47) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| Fluoride Ion SCHEMBL5148077 | 0.82 | KMT2A (0.47) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL11383237 | 0.82 | USP2 (0.50) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| Bromide SCHEMBL8588064 | 0.80 | HSP90AA1 (0.45) | NPSR1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL9811156 | 0.80 | L3MBTL1 (0.61) | NPSR1L3MBTL1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870495-A1 | Aqueous alkaline, cyanide-free, bath for the galvanic deposition of Zinc and Zinc alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2007-12-26 | — | — | EP | disclosed |