Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.51 |
| ▸ | HRH2 | P25021 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489610 | 0.80 | MCHR1 (0.46) | MEN1ALDH1A1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL647375 | 0.76 | HRH3 (0.57) | HRH3HRH2HRH1MEN1ALDH1A1 | |
| SCHEMBL21776404 | 0.71 | ABCB1 (0.41) | HRH3HRH2HRH1MEN1ALDH1A1 | |
| SCHEMBL5484625 | 0.68 | MMP3 (0.50) | ALDH1A1KCNH2 | |
| SCHEMBL27969433 | 0.68 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2PIN1KCNH2 | |
| SCHEMBL8354514 | 0.67 | MEN1 (0.49) | HRH3MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3503161 | 0.66 | MMP3 (0.48) | ALDH1A1KCNH2 | |
| SCHEMBL12420832 | 0.66 | ALDH1A1 (0.70) | MEN1ALDH1A1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL5444736 | 0.66 | MAPT (0.55) | MEN1ALDH1A1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL5185511 | 0.66 | HRH3 (0.44) | HRH3HRH2HRH1KCNH2USP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |