Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580840 | 0.80 | ALDH1A1 (0.41) | TSHRMAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL8174336 | 0.77 | NPC1 (0.55) | MAPK1MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11382303 | 0.76 | ALDH1A1 (0.50) | MAPTALDH1A1CYP1A2SMN1; SMN2GAA | |
| SCHEMBL28103257 | 0.75 | MAPT (0.48) | NOS1MAPK1TSHRMAPTMAOB | |
| SCHEMBL7035059 | 0.73 | MAPK1 (0.53) | NOS1MAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL27793083 | 0.72 | RAB9A (0.52) | MAPTALDH1A1TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11812108 | 0.71 | ALDH1A1 (0.50) | NOS1MAPK1TSHRMAPTMAOB | |
| SCHEMBL874309 | 0.71 | MAPK1 (0.55) | NOS1MAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL2103568 | 0.71 | MAPK1 (0.55) | NOS1MAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL8665732 | 0.70 | ALDH1A1 (0.50) | NOS1MAPK1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |